Mendelian Randomization

Mendelian randomization is a study design that uses genetic variants as instrumental variables to test the causal effect of a (non-genetic) risk factor on a disease or health-related outcome. Since its first proposal in 2003, academics working in the MRC Integrative Epidemiology Unit (IEU) and throughout Population Health Sciences at the University of Bristol Medical School (including those who are tutors on this course) have been at the forefront of developing methods for assessing and limiting potential biases with this approach.

Dates 20 - 23 February 2024
Fee £770
Format Online
Audience Open to all applicants (prerequisites apply)

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This course aims to provide an introduction to the conduct, assumptions, strengths and limitations of Mendelian randomization, including the use of up-to-date methods for sensitivity analyses that explore likely violation of Mendelian randomization assumptions.

Please click on the sections below for more information. 

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What a brilliant group of tutors! The pace was great, the reading materials comprehensive, the interactive practical sessions. They made learning MR in 3 days less daunting. If anyone would have told me that I would be able to learn almost every aspect or MR in 3 days, I would have never believed them but I did, thanks to an amazing group of tutors.

Course feedback, December 2022

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Find out about the self-paced Materials & Recordings version of this course [UoB only].

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