Specialist facilities and services

The University has a number of high-spec, state-of-the-art facilities that are technically supported and available for use by external researchers and industry, search the list below for services or equipment.

If Bristol does not offer the service you require, try the wider regional Universities community - the GW4 partnership

Name Overview Contact Equipment Equipment
Clinical Animal Behaviour Group
  • Veterinary services
  • Animal welfare
  • Behaviour consultation
  • Referring clinical cases
  • Residency programme
  • Separation related behaviours

Clinical Behaviour Office

Langford-behaviour@bristol.ac.uk

   

Cleanroom

(TRAC Facility)

  • Several class-1000-rated rooms
  • Wafer-scale micro and nano fabrication
  • Houses process tools for lithography, dry etch, deposition, chemical processing, post processing and characterisation
  • Rapid prototyping of a range of devices, including photonic structures, microfluidics, micro-lenses, integrated circuits and MEMS

See Contacts on right hand side of Cleanroom page.

For a full and up to date equipment list, see the Cleanroom page.  

Nuclear Magnetic Resonance Facility

(TRAC Facility)

Biological NMR:

  • High-field Nuclear Magnetic Resonance spectrometry
  • Protein and small molecule structure analysis
  • Protein-ligand binding studies

Chemical NMR:

  • Solution state Nuclear Magnetic Resonance spectrometry of small molecules
  • Multinuclear and diffusion NMR
  • Molecular structure and mixture analysis

Matt Crump (Biological NMR)

Matt.Crump@bristol.ac.uk

 

Craig Butts (Chemical NMR)

Craig.Butts@bristol.ac.uk

 

 

Chemical:

  • Bruker 700 MHz spectrometer with 1.7 mm cryoprobe
  • Bruker Avance 400
  • Bruker Avance 300
  • Bruker 500 MR NMR Spectromer  with 13C cryoprobe
  • JEOL Eclipse 300 NMR Spectrometer
  • JEOL ECS 400 NMR Spectrometer
  • JEOL ECS 300 NMR Spectrometer
  • Varian 400 MR NMR Spectrometer
  • Varian 500 VNMRS NMR Spectrometer
  • Varian INOVA 600 MHz NMR Spectrometer
  • Varian VNMRS 600 spectrometer with cryoprobe 

 

 

Bristol Genomics Facility
  • DNA and RNA sequencing, analysis and quality assessment
  • Microarray expression analysis
  • High-throughput Genotyping
  • Real-time quantitative PCR
  • Capillary sequencing and genotyping
  • Bioinformatic support

Genomics Facility

genomics-facility@bristol.ac.uk

For a full and up to date equipment list, visit the Bristol Genomics Facility page and explore the 'Our services' menu on the right.

 

 

Bristol NanoESCA Facility

(TRAC Facility)

  • High-resolution surface chemical state analysis
  • Photoemission electron microscopy (PEEM)
  • Multichannel XPS
  • SPA-LEED
  • Imaging and spectroscopy/diffraction modes
  • Low energy electron diffraction
  • Specialist light sources
  • In situ annealing and sputtering
  • UHV suitcase
  • Materials analysis

Bristol NanoESCA Facility

info-nanoesca@bristol.ac.uk

Scienta Omicron NanoESCA II monochromated x-ray source

 

Centre for Nanoscience and Quantum Information (NSQI)
  • Purpose built low noise and ultra-low noise labs achieving vibration levels lower than the lowest recognised criteria (Vibration Criteria G – VC-G) plus protection from electrical noise
  • Soundproof chamber
  • Class 1000 clean room
  • Technically supported
  • Sample preparation laboratories

 Contacts and how to find us

 

 

Electron and scanning probe microscopy

(TRAC Facility)

  • Scanning electron microscopy (SEM)
  • Transmission electron microscopy (TEM)
  • Atomic force microscopy (AFM)
  • Nanoscale imaging and analysis
  • Full technical and training support
  • Chemical imaging and analysis

Sean Davis  

S.A.Davis@bristol.ac.uk 

  • JEOL 200 Kv Field Emission Gun TEM 2100F with STEM
  • Electron diffraction
  • Gatan digital camera
  • Oxford Instruments Energy Dispersive X-ray analysis system (80mm2 SSD; Aztec)
  • Gatan Cryo holder and heating holder
  • JEOL 120 Kv 1400 TEM with Gatan digital camera
  • JEOL 120 Kv 1200 Mk2 TEM with SIS digital camera
  • JEOL SEM IT300 LV with Oxford Instruments Energy Dispersive X-ray analysis system (80mm2 SSD; Aztec)
  • JEOL Field Emission Gun SEM 6330 with Gatan Cathodoluminescence and Oxford Instruments Energy Dispersive X-ray analysis
  • Bruker Multimode 3 with Quadrexed Nanoscope 3D controller
  • Bruker Multimode 8 PeakForce QNM allowing conductivity and quantitative material property (including modulus, adhesion, deformation, and dissipation) mapping
  • Vacuum coating (C and Pt/Pd, Au)
  • Ultramicrotomy
  • Critical point drying and freeze-drying

 

Mass Spectrometry

(TRAC Facility)

  • Mass spectrometry
  • Chemical mass spectrometry
  • Material analysis
  • HPLC-MS/UPLC-MS
  • LC-MSn
  • Nano-LC-MS
  • IMS-MS
  • Accurate mass, EI, CI, ESI, nanospray and Maldi MS

Paul Gates

Paul.Gates@bristol.ac.uk

  • Thermo Scientific Orbitrap Elite High resolution (MSn) mass spectrometer with UPLC/HPLC.
  • Waters Synapt G2S IMS-TOF mass spectrometer with Nanomate source.
  • Bruker Daltonics UltrafleXtreme 2 High resolution MALDI-TOF/TOF mass spectrometer.
  • Bruker Daltonics micrOTOF Focus II High resolution TOF mass spectrometer.
  • Applied Biosystems 4700 Proteomics MALDI-TOF/TOF mass spectrometer.
  • Bruker Daltonics Esquire 6000 Ion-trap mass spectrometer with HPLC.
  • VG Autospec 3 sector (double focussing) mass spectrometer 
 

 

Electron Microbeam Laboratories

(TRAC Facility)

  • Nanoscale imaging and quantitative compositional analysis
  • Materials analysis
  • Training in Electron Microscopy and X-ray microanalysis methods
  • Spectroscopy

Stuart Kearns

Stuart.Kearns@bristol.ac.uk

 

  • Hitachi S-3500N variable pressure microscope equipped with Thermo Noran energy dispersive spectrometer (EDS x-ray detector)
  • Environmental secondary electron detector (ESED) and BSE detector, JEOL JXA8530F Hyperprobe (EPMA)
  • Field Emission Gun electron source
  • Cameca SX100 microprobe
  • 5 wavelength dispersive spectrometers
  • Energy dispersive spectrometer
 
Histology Services Unit
  • Histochemistry
  • Fresh and fixed, frozen sectioning
  • Fixation and staining
  • Wax processing
  • Immunocytochemistry
  • Immunofluoresent staining
  • Image capture
  • Consultancy
  • Clinical studies

See Contacts at bottom of Histology Services page.

  • Cryostat x4.
  • Sliding microtome with peltier cooling x1.
  • Rotary microtomes x4.
  • Thermo Excelsior processor.
  • Medite TP15 processor.
  • Medite embedding centre.
  • Slide printer.
  • Cassette printer.
  • Leica DM750 microscope with integral digital camera.
  • Motik SMZ-168 dissecting microscope with integral digital camera with bespoke thermal stage for orientation of wax embedded tissue.
  • Vast range of stains.
  • 10L Liquid nitrogen dewar.
  • Virtual Microscope.
  • Shandon knife sharpener.

 

Aqueous Geochemistry ICP-OES
  • Inductively Coupled Plasma – Optical Emission Spectrometry
  • Trace analysis of aqueous solutions
  • Metal, CA, Na and K ion detection
  • Soil leachate analysis
  • Spectroscopy

See Contact at bottom of Aqueous Geochemistry page.

Agilent 710 ICP-OES, Inductively Coupled Plasma Optical Emission Spectrometer  
Illumina Facility
  • Illumina microarray processing and expertise
  • Methylation analysis
  • DNA analysis
  • SNP genotyping arrays
  • Bioinformatics support
  • Dedicated Biobank storage facility

bbl-arrays@bristol.ac.uk

 Illumina iscan, autoloader and array processing robot  

Interface Analysis Centre - Techniques & Analytical Methods

(TRAC Facility)

  • Materials analysis
  • Focused Ion Beam (FIB)
  • Electron and Optical microscopy
  • Spectroscopy
  • X-ray diffraction
  • Thermogravimetric Calorimetry (DSC)
  • Imaging
  • High-Speed Atomic Force Microscopy

See Contacts on right hand side of IAC techniques & analytical methods page.

For a full and up to date equipment list, see the IAC's Techniques & analytical methods page.

 

Langford Vets
  • Veterinary services
  • Animal welfare
  • Diagnostic Laboratories
  • Farm Animal Practice
  • Small Animal Hospital
  • Stables Equine Practice

Langford Vets Contact Page

  • State of the art diagnostic imaging facilities including X-rays, ultrasound scans, Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) scanning.
  • Quantitative real-time PCR
  • TB testing
  • Laboratory and post-mortem facilities
 
Mycoplasma Testing Service
  • Clinical studies
  • Cell culture
  • Cell Line Authentication
  • Repository Production
  • Over Passaging of Cells
  • Cross Contamination
  • Infection Identification and Control
  • Quarantine

Sue Christie

sue.christie@bristol.ac.uk

   
Proteomics Facility
  • Protein Separation
  • Protein identification
  • Quantitative Proteomics (SILAC, TMT)
  • Phosphoproteomics
  • Serum Proteomics
  • LC-MS service

See Proteomics Facility Contacts Page

  • Orbitrap Fusion Tribrid Mass Spectrometer with up-stream Ultimate 3000 nano-LC system (Thermo Scientific)
  • LTQ-Orbitrap Velos Mass Spectrometer with up-stream Ultimate 3000 nano-LC system (Thermo Scientific)
  • DigestPro automated digestion unit (Intavis Ltd.)
  • 2 x Ultimate 3000 stand alone LC systems for peptide fractionation (Thermo Scientific)
  • GE Healthcare IPGphor3 Isoelectric Focussing Units
  • GE Healthcare Ettan DALT Twelve and Six Separation Units
  • GE Healthcare DALT Twelve Gel caster
  • GE Healthcare Typhoon 9400 Variable Mode Imager

 

Faculty of Science  Workshops

(Service)

  • Mechanical, glass and electrical engineering
  • Design, prototyping, manufacture, modification, repair and testing
  • High and ultra-low vacuum
  • Cryogenics

See Faculty of Science Workshops Contacts Page

  • Water jet cutting
  • CNC milling
  • Manual milling and turning
  • Comprehensive fabrication facilities including laser, MIG/TIG and MMA welding
  • Traditional scientific glass blowing and manufacturing equipment
  • Glass diamond saws and grinders
  • Laser cutter
  • 3D printer
 
Wolfson Bioimaging Facility
  • Latest-state-of-the-art light/optical and electron microscopy
  • Cell and life sciences imaging for biological and biomedical research

See Wolfson Bioimaging Facility Contacts Page

  • Leica SP5 confocal imaging systems (3, incl 1 with resonant scanner and hybrid detectors)
  • 2 Leica SP8 confocal systems (with resonant scanner and hybrid detectors)
  • Leica SPE confocal system
  • Ultraview Spinning Disk
  • Widefield imaging systems (6, various specs)
  • Leica TIRF microscope
  • Leica SP8 Multiphoton
  • Leica SP8 Fluorescence lifetime imaging microscope
  • Leica SP8 STED (super-resolution)
  • Leica SP8 fluorescence correlation spectroscopy
  • Perkin Elmer Opera LX high content screening system
  • Essen IncuCyte high throughput live cell imaging system
  • Tecnai 12 -FEI 120kV BioTwin Transmission Electron Microscope (TEM)
  • Tecnai 20 -FEI 200kV LaB6 Twin Lens Transmission Electron Microscope (TEM) including HAADF-STEM detector and cryo capabilities
  • Quanta 400FEI FEG Scanning Electron Microscope (SEM) with cryo attachment
  • Vitrobot
  • High Pressure Freezer, Leica EMPACT2 + RTS
  • Cryo-ultramicrotome
  • Ultramicrotome
  • Photo-oxidation light microscope (Correlative Microscopy)
  • Cryo fluorescence Light Microscope (Correlative Microscopy) 

 

GW4 cryo-EM facility
  • Advanced technology and expert support for high resolution electron cryo-microscopy.

See 'Access the facility' page to make an enquiry

 

 
Flow cytometry
  • High speed digital benchtop cytometers and a state of the art Fluorescence Activated Cell Sorter (FASC) 

See details on the right of the Flow cytometry page

For an up to date description of equipment see the Flow cytometry page  
BioSuite Facility
  • A custom-built facility that supports microbial cell culture and protein production.

See the BioSuite Facility page to make an enquiry

For a full and up to date list of equipment see the BioSuite Facility page  
Clinical Research Imaging Centre (CRIC)
  • CRIC Bristol provides key facilities for clinicians and academics to deliver cutting-edge research and improved patient care.
     

X-ray crystallography

(TRAC Facility)

  • Single crystal X-ray structure determination/analysis (90-400K)
  • Absolute structure determination
  • Routine powder X-ray diffraction measurements
  • Variable temperature powder X-ray diffraction measurements (16-300K)

Hazel Sparkes

hazel.sparkes@bristol.ac.uk

  • Bruker D8 Advance Powder Diffractometer
  • Bruker Microstar Rotating Anode Copper Diffractometer
  • Bruker Kappa Apex II Molybdenum sealed tube single crystal diffractometer
 

 

X-ray Tomography (XTM) Facility

(TRAC Facility)

  • Micro-CT X-ray imaging
  • 3D imaging and analysis
  • Imaging suite workstations and software for 3D visualisation and analysis

See contact on right hand side of X-ray Tomography (XTM) Facility page, under 'Quotes, booking and information'.

  • Nikon XT H 225 ST CT scanner
  • Imaging lab with high spec workstations and software for 3D visualisation and analysis of tomographic datasets
 

 

UKCRIC Soil-Foundation-Structure Interaction Laboratory  
  • Engineering
  • Soil-structure interaction
  • Seismic qualification
  • Vibration testing
 uob-sofsi@bristol.ac.uk
  • 6m x 4m 2g biaxial seismic shaking table with 50 tonne payload capacity
  • 1.2m x 1.2m 6-degree-of-freedom 8g shaking table with 500kg payload capacity
  • 6m x 5m x 4m deep soil test pit with surrounding strong floor for bespoke placement of multiple actuators up to 1Mn
 
         
Earthquake and Large Structures (EQUALS) Laboratory  
  • Engineering
  • Seismic qualification
  • Vibration testing
  • Structural testing
See Earthquake and Geotechnical Contacts Page.
  • 3x3m 6-degree-of-freedom 5g shaking table with 15 tonne payload capacity
  • Strong floor and reaction walls and hydraulic actuator portfolio for bespoke test set-ups

 

 
Aerodynamic and aeroacoustic facilities  
  • Engineering
  • Aeroacoustics
  • Aerodynamics
  • Propeller testing
See Contact on right hand side of Aerodynamic and aeroacoustic facilities Page, under 'More information'.
  • 7x5ft Closed Test Section Wind Tunnel with speeds of up to 60m/s.
  • Low Turbulence Wind Tunnel designed for faster speed testing up to 100m/s, equipped with particle image velocimetry equipment (PIV) and a test section of approximately 0.8m x 0.6m.
  • Aero acoustic Wind Tunnel, an anechoic chamber approximately 7m x 4.5m x 3.5m and fully anechoic down to 160Hz, this has a velocity range of 8m/s to 12m/s.
  • The pressure-neutral acoustic wind tunnel is a closed-loop, open section wind tunnel. With a velocity range of 5m/s to 35m/s.
  • Currently being built Boundary Layer Wind Tunnel, with a test section which will span over 18m in length and capable of creating a boundary layer of 25cm thick.
  • Jet noise facility allows a flow of compressed air of between Mach 0.1 and 1.4.

 

 

Bristol Radiocarbon Mass Spectrometry Facility (BRAMS)

(TRAC Facility)

  • The MICADAS accelerator mass spectrometer is a high-precision and compact instrument that is capable of measuring radiocarbon dates on even the tiniest of samples.
  • It is capable of analysing samples as both graphite targets and CO2 gas, with applications ranging from archaeology through to palaeoclimatology, past and present environmental studies, and geosciences.

 

Tim Knowles

tim.knowles@bristol.ac.uk

   
Analytical Laboratory (Geographical Sciences) Unique national research facility with state-of-the-art instrumentation focused on biogeochemical processes in aquatic and terrestrial systems, including low temperature environments.

Bespoke analytical and consultancy services upon request.

Fotis Sgouridis

f.sgouridis@bristol.ac.uk

   

Please note that this page is currently under review and is being temporarily managed by Dr Caroline Jarrett. To request changes, please email Caroline with the details.

Edit this page