Understanding Trusted Research Environments

Advances in data science including a commitment to reproducible science through open standards, data and source code have resulted in different ways of working within research. Trusted Research Environments are in many cases now the default pathway to accessing data, representing a step change in how data is accessed for research and introducing new challenges. The tutors on this course have been at the forefront of these developing approaches, both through applied research and the development of infrastructure. The University of Bristol (with the University of Edinburgh) run the UK Longitudinal Linkage Collaboration (UK LLC), a trusted research environment bringing together information from the longitudinal study volunteers with their routine records.

Dates 22 - 26 April 2024
Fee £0 (pilot course)
Format Online
Audience Internal University of Bristol only, pilot course (prerequisites apply)

This internal course is open to UoB staff and students only.  If you are unsure whether you are eligible to attend please contact us.

Image of white lines running across a red background Course profile

This course will introduce some exemplar TREs (e.g. The UK Longitudinal Linkage Collaboration (UK LLC), NHS England TRE and OpenSAFELY) to highlight the different ways TREs function, and some of the strengths and challenges these environments can introduce to research such as the availability of different tools. Different approaches to working within TREs will also be covered including insight into the strengths and challenges of different tools that can be used to manipulate data, conduct analyses, and create safe research outputs.

We aim to equip researchers with the confidence to work within TREs through awareness of the benefits, challenges and differences that exist across TREs. This course will not provide detail of analytic techniques but will instead provide awareness and understanding of the steps that need to be taken before analysis can be undertaken and once analysis is complete. These include applying to the TRE for access to data, deriving codeslists, creating cohorts, quality assurance, through to the close of the research project including requesting safe outputs for publication, and producing appropriate documentation for uploading to packages such as GITHub.

Whilst we will also more broadly introduce other important aspects of working within TREs including governance and data standards; common approaches to dealing with known challenges; the importance of patient and public involvement and engagement including fair processing and transparency; the benefits of developing good practice in documentation not least to support reproducible research. Emphasis is placed on working to open research practices supporting accessible, transparent, reproducible and visible research


Please click on the sections below for more information:

Web banner in red and white with the text Bristol Medical School Short Courses Bookings for this course are now closed

Edit this page