Electron microscopy

The Electron Microscopy (EM) unit at the Wolfson Bioimaging Facility houses an extensive range of advanced microscope systems for imaging cells, tissues, organisms and materials.

Our excellent facilities include two transmission electron microscopes (TEMs) and three scanning electron microscopes (SEM). We also have capability for volume EM allowing 3D analysis of specimens and an extensive range of processing equipment.

Our support team provides advice, support and training for standard electron microscopy protocols and specialised techniques such as cryo-electron microscopy (cryo TEM), scanning transmission electron microscopy (STEM), electron tomography, immunolabelling and correlative light and electron microscopy (CLEM).

Please contact one of the team to discuss projects, arrange training or for advice on sample preparation, image acquisition and analysis.

In 2017 the GW4 facility for high-resolution electron cryo-microscopy (FEI Talos Artica) was established in the Life Sciences Building and is affiliated with the Wolfson Bioimaging Facility.

 Side-by-side microscopy images: left shows a grayscale electron micrograph of cellular ultrastructure with layered membranes; right shows a scanning electron micrograph of rod-shaped bacteria highlighted in purple among filament-like structures.