The Wolfson Bioimaging Facility underpins international-quality research across the University of Bristol and further afield.
By providing a broad range of advanced imaging technologies encompassing and linking light and electron microscopy, the Facility supports many research areas, including:
- Cardiovascular Science
- Cell Biology
- Infection and Immunity
- Synthetic Biology
Our user base currently encompasses over 300 researchers from a wide range of disciplines in the biomedical and physical sciences across the University. The impact and scope of the Wolfson Bioimaging Facility is seen in over 700 research publications that include data acquired on our microscopes.
We advise and train researchers at all levels of their careers to optimise the use of our microscope systems and to process and analyse the data they generate.
Recent publication highlights
- Live imaging of wound angiogenesis reveals macrophage orchestrated vessel sprouting and regression. EMBO J. doi: 10.15252/embj.201797786 (2018)
- Non-muscle Myosin II drives vesicle loss during human reticulocyte maturation. Haematologica doi: 10.3324/haematol.2018.199083 (2018)
- Long-range exciton transport in conjugated polymer nanofibers prepared by seeded growth. Science 360: 897-900 (2018)
- Light-induced dynamic structural color by intracellular 3D photonic crystals in brown algae. Science Advances 4(4): eaan8917 (2018)
- Bioinspired silicification reveals structural detail in self-assembled peptide cages. ACS Nano 12:1420-1432 (2018)
- Nanoparticle-induced neuronal toxicity across placental barriers is mediated by autophagy and dependent on astrocytes. Nature Nanotechnology 13: 427-433 (2018)
- Fat body cells are motile and actively migrate to wounds to drive repair and prevent infection. Developmental Cell 44: 460-470 (2018)
- Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis. JCI Insight 10.1172/jci.insight.99062 (2018)
- Fabrication of micropatterned dipeptide hydrogels by acoustic trapping of stimulus-responsive coacervate droplets. Small 14(26):e1800739 (2018)
- Engineered synthetic scaffolds for organizing proteins within the bacterial cytoplasm. Nature Chemical Biology 14:142-147 (2018)
- A transient pool of nuclear F-actin at mitotic exit controls chromatin organization. Nature Cell Biology 19:1389-1399 (2017)
- Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling. Nature Cell Biology 19:1214-1225 (2017)
- Higher-order assembly of crystalline cylindrical micelles into membrane-extendable colloidosomes. Nature Communications 8:426. (2017)
- PICK1 regulates AMPA receptor endocytosis via direct interactions with AP2 α-appendage and dynamin. Journal of Cell Biology 216: 3323-3338. (2017)
- Sequence-dependent cargo recognition by SNX-BARs mediates retromer-independent transport of CI-MPR. Journal of Cell Biology 216: 3695-3712. (2017)
- Metabotropic action of postsynaptic kainate receptors triggers hippocampal long-term potentiation. Nature Neuroscience 20: 529-539 (2017)
- Decorating self-assembled peptide cages with proteins. ACS Nano 11:7901-7914(2017).
- Predatory behaviour in synthetic protocell communities. Nature Chemistry 9, 110-119 (2017.
- Two-dimensional assemblies from crystallizable homopolymers with charged termini. Nature Materials 16: 481-488 (2017)
Fat body cells are motile and actively migrate to wounds to drive repair and prevent infection. Developmental Cell 44: 460-470 (2018)
Long-range exciton transport in conjugated polymer nanofibers prepared by seeded growth. Science 360: 897-900 (2018)
Bioinspired silicification reveals structural detail in self-assembled peptide cages. ACS Nano 12:1420-1432 (2018)