New drug formulation could treat Candida infections28 April 2020With antimicrobial resistance (AMR) increasing around the world, new research led by the University of Bristol has shown a new drug formulation could possibly be used in antifungal treatments against Candida infections.
Catalytic protocells get zingy8 January 2020Artificial cells capable of oxygen gas production and chemical signalling have been prepared using a combination of synthetic and biological catalysts through an international collaboration between the University of Bristol and the University of Padua in Italy.
Scientists discover body’s protection shield18 November 2019Scientists have discovered a way to manipulate the body’s own immune response to help boost tissue repair. The findings, published in Current Biology today [18 Nov], reveal a new network of protective factors to shield cells against damage. This discovery, made by University of Bristol researchers, could significantly benefit patients undergoing surgery by speeding recovery times and lowering the risk of complication
Powerful new synthetic vaccines to combat epidemics25 September 2019A new type of vaccine that can be stored at warmer temperatures, removing the need for refrigeration, has been developed for mosquito-borne virus Chikungunya in a major advance in vaccine technology. The findings, published in Science Advances today [Wednesday 25 September], reveal exceptionally promising results for the Chikungunya vaccine candidate, which has been engineered using a synthetic protein scaffold that could revolutionise the way vaccines are designed, produced and stored.
Putting the squeeze on red blood cells11 September 2019For the first time, researchers at the University of Bristol’s Blood and Transplant Research Unit, and the French National Institute for Blood Transfusion, have captured the moment a red blood cell is ‘squeezed’ while recording the changes that allow it to deform and subsequently recover its shape.
Scientists reveal how a faulty gene leads to kidney disease15 August 2019New insights into why a faulty gene involved in a devastating form of a kidney condition called nephrotic syndrome leads to disease in some patients have been identified in new Kidney Research UK-funded research led by the University of Bristol. The findings, published in the Journal of the American Society of Nephrology (JASN), could pave the way for new ways to prevent or treat the condition, by revealing new targets to intervene in the process. Around 1 in 50,000 children are diagnosed with nephrotic syndrome each year.
Shape shifting protocells hint at the mechanics of early life 25 July 2019Inspired by the processes of cellular differentiation observed in developmental biology, an interdisciplinary team of researchers at the University of Bristol have demonstrated a new spontaneous approach to building communities of cell-like entities (protocells) using chemical gradients.