How your internal microbes can keep you healthy11 June 2020There is a vast community of bacteria, viruses and fungi living on your body right now; collectively they are known as the human microbiome; they have hugely greater complexity than the human genome itself. The microbiome, which mostly lives in the gut, plays an important role in immunity, defense against pathogens, increasing availably of nutrients to the host (that’s you and me), and even influencing health and behaviour. Although how the microbiome affects our health and behaviour (or vice versa) is not particularly well understood.
Screen time and anxiety in adolescence11 June 2020Modern teenagers spend vastly more time in front of screens than their forebears ever did - and there is also an increase in reports of anxiety disorders amongst the age same group. It seems, obvious, therefore, that the one must directly influence the other. But is that so?
Probing new treatments for post-operative kidney problems20 April 2020Kidney transplants - especially in children are always fraught with risk. In up to 10% of cases, transplants into young children fail because of graft thrombosis - an issue with the blood supply to the new kidney. At present, the only way doctors know that this is happening is because the patient’s condition starts to deteriorate - and at this point, successful intervention and treatment is unlikely. What is needed is a minimally invasive probe, which would be able to monitor the perfusion of the kidney in real time.
Emergency anaesthesia under the spotlight30 March 2020Emergency surgery is a procedure beset with risks; many of these concern the use of anaesthetics. Dr Lucy Elliott, a medic with the North Bristol NHS Trust, is using the Clinical Primer Scheme from the Elizabeth Blackwell Institute to find ways to minimise the dangers.
Bridging Fund helped to secure £1 million award12 March 2020A Research Fellow at the Centre for Academic Child Health at the University of Bristol’s Medical School used a Bridging Fund from Elizabeth Blackwell Institute to help secure a five-year MRC Career Development Award worth over £1 million.
A single gene with large implications for rare blood disease11 March 2020A researcher at the University of Bristol has used next-generation sequencing technologies to identify a completely new way that faults in a gene result in a rare blood disorder, thanks to funding from the Elizabeth Blackwell Institute.
Could robotic implants treat Stress Induced Incontinence?18 February 2020Stress urinary incontinence is a distressing problem which is common for women following pregnancy, childbirth or the menopause. It affects at least 200 million women worldwide, although it’s rarer in men. Researchers at the University of Bristol are investigating whether it might be possible to implant a soft robotic device to more successfully control urine flow.
Heart insight - glaucoma drug’s potential for cardiac treatment21 January 2020Every three minutes, someone in the UK suffers a heart attack. Although 100,000 people die from coronary heart disease, ten times more people suffer a non-fatal attack. Researchers at the University of Bristol have uncovered a new use for acetazolamide, a drug previously used to treat glaucoma, as a treatment for heart attack patients.
Strokes and the ageing brain8 January 2020With advancements in medicine, the world’s population is living longer, and age-related diseases are becoming more and more prevalent; the diagnostic technologies we have need to keep pace with our changing requirements. A University of Bristol researcher developed new approaches with MRI and disease modelling to further understand the ageing process, and how it can relate to disease states.
Can xenon help protect against neonatal brain damage?8 January 2020Hypoxic-ischæmic encephalopathy (HIE) is brain damage caused by limited blood flow - and thus oxygen deprivation - in newborn babies, at or around the time of birth. A team at the University of Bristol is working towards new treatments for babies with birth-caused brain damage.
Clinicians and researchers come together to develop new test for blood disorder7 January 2020Researchers at the University of Bristol are working on a new test to help treat a debilitating blood disorder, immune thrombocytopenia. Dr Charlotte Bradbury, consultant senior lecturer in the department of Haematology at the University of Bristol, submitted a challenge to researchers via the Elizabeth Blackwell Institute Research for Health scheme, which aims to pair up scientists and clinicians with an unmet need.