Completed trials

AIRWAYS-2 Airway Management in cardiac arrest patients

Apex Two RCT’s of peri-operative wound infiltration with local anaesthetic

Arena Feasibility study for an RCT of physiotherapy after knee replacement

Best-BRA Is subpectoral or pre-pectoral implant placement Best in immediate BReAst reconstruction?

Bluebelle Feasibility of three wound dressing strategies in elective and unplanned surgery

CHEMORAD Feasibility trial of chemoradiation or surgery for oesophageal cancer: Oesophageal squamous cell cancer: chemoradiotherapy versus chemotherapy and surgery

Cortisol Ultradian Rhythms of Cortisol after Cardiac Surgery

Cortisol 2 Cortisol profiles in the critically ill after cardiac surgery

eRAPID Towards safer delivery and monitoring of cancer treatments. Electronic patient self-Reporting of Adverse-events

FAB Fractures and Bisphosphonates: A double-blind, randomised controlled trial on the effect of alendronic acid on healing and clinical outcomes of wrist fractures. Arthritis Research UK ref. 19403
HAND-1 Needle fasciotomy versus limited fasciectomy for the treatment of Dupuytren’s contractures of the fingers: a study which investigates the feasibility, acceptability and design of a multicentre RCT
Harvest Factorial RCT to assess the extent of intimal hyperplasia and atherogenesis in bypass vein grafts following different surgical preparation techniques

IMPROVE trial Can emergency endovascular aneurysm repair (eEVAR) improve the survival from ruptured abdominal aortic aneurysm?

INFORM NIHR funded programme grant including a multicentre RCT of surgical treatment of infection

INSPIRE Effectiveness and cost-effectiveness of INSPIRatory musclE training (IMT) for reducing postoperative pulmonary complications (PPC): a sham-controlled randomised controlled trial (RCT)

Investigating RIPC A 2-centre RCT investigating the effect of remote ischemic preconditioning (RIPC) on blood and myocardial biomarkers of stress and injury-related signaling in patients having isolated coronary artery bypass grafting (CABG) or aortic valve replacement (AVR) using cardiopulmonary bypass (CPB) preconditioning

INVITE The effectiveness on post-operative recovery of using ‘off pump’ self-expanding tissue valves (IPVR) versus ‘on pump’ conventional tissue valves (PVR) for pulmonary valve replacement: an early phase RCT 

MALIT A Multicentre RCT of Splint Duration for Mallet Injuries

MASTER Male synthetic sling versus Artificial urinary Sphincter Trial for men with urodynamic stress incontinence after prostate surgery: Evaluation by Randomised controlled trial

Oxic-2 RCT to compare normoxic vs. standard cardiopulmonary bypass in cyanotic children having cardiac surgery

Pasport Patient-specific cerebral oxygenation monitoring as part of an algorithm to reduce transfusion during heart valve surgery

Prompt RCT of propofol cardioplegia on blood and myocardial biomarkers of stress and injury in patients having isolated CABG or aortic valve replacement using cardiopulmonary bypass

ProtecT Prostate Testing for Cancer and Treatment

Protection 1 Pulmonary protection with low frequency ventilation during cardiopulmonary bypass

RESTORE Improving patients' experience and outcome of total joint replacement

ROCS Radiotherapy after Oesophageal Cancer Stenting study

ROLO The reno protective value of leukodepletion in heart valve surgery: an external feasibility RCT

ROMIO Randomised oesophagectomy: minimally invasive or open

SCAT Shortening Cardioplegic Arrest Time During Combined Coronary and Valvular Surgery: A Single-Centre RCT

Spiral Feasibility study for an RCT of a patient education tool for advanced osteoarthritis

STAR Support and Treatment after joint Replacement. Evaluation of a care pathway for patients with long-term pain after knee replacement

TEMPLATE A RCT Investigating the Pharmacodynamic Effect of Ticagrelor Monotherapy on Platelet Reactivity in Patients with Coronary Artery Disease

Thermic-2 RCT to compare normothermic vs. hypothermic cardiopulmonary bypass in children having open heart surgery
Titre 2 Transfusion Indication Threshold Reduction on transfusion rates, morbidity and healthcare resource use following cardiac surgery
Transact-1 Transplantation of enriched autologous bone-marrow derived CD 133 cells in patients having coronary surgery after STEMI
UNBLOCS A randomised controlled trial to determine the clinical and cost effectiveness of thulium laser transurethral vaporesection of the prostate (ThuVARP) versus transurethral resection of the prostate (TURP) in the National Health Service
Verdict Preoperative volume replacement vs. usual care in diabetic patients having CABG surgery
VICI RCT efficacy and mechanistic evaluation of Eplerenone for central serous chorioretinopathy
VIOLET VIdeo assisted thoracoscopic lobectomy versus conventional Open LobEcTomy for lung cancer, a multi-centre randomised controlled trial with an internal pilot
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