
Professor Gavin Welsh
B.Sc., Ph.D.(Bristol)
Current positions
Professor of Renal Cell Biology
Bristol Medical School (THS)
Contact
Press and media
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Research interests
Gavin Welsh graduated with a degree and a PhD in Biochemistry from the University of Bristol. After 4 further years at Bristol doing postdoctoral research he spent 2 years at the University of Kent at Canterbury before being awarded an EMBO Long Term fellowship to work for 2 years in the Virology and Cellular Immunology Unit at the Institute Pasteur, Paris, France. Gavin then moved back to the University of Bristol working for 6 years as a research fellow in the Department of Biochemistry. He is currently a Reader in Renal Cell Biology in Bristol Renal. His research interests centre on renal cell signaling and how this is altered in disease states especially in Nephrotic Syndrome and Diabetic Nephropathy.
Projects and supervisions
Research projects
Modification of AAV capsids for effective renal gene therapy
Principal Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
15/11/2021 to 11/02/2022
P MATHIESON 2% CO-I MANCHESTER UNI
Principal Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
01/04/2012 to 01/04/2015
Understanding the pathogenesis of haemolytic uraemic syndrome
Principal Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
16/08/2010 to 16/08/2013
Thesis supervisions
Investigating the trigger for human parturition using metabolomic and phosphoproteomic techniques within case-control and cohort studies
Supervisors
The role of p21-activated kinase in hippocampal synaptic function
Supervisors
Investigation of novel biomarkers and treatment strategies in steroid-resistant nephrotic syndrome
Supervisors
Investigating Adeno-Associated Virus as a Vector for Gene Therapy for Steroid-Resistant Nephrotic Syndrome
Supervisors
Effects of disease-causing mutations of podocin on podocyte biology
Supervisors
Towards the 3D Biofabrication of a Glomerular Filtration Barrier
Supervisors
Understanding the Pathogenesis of Nephrotic Syndrome - Studying Signaling Pathways in Response to Nephrotic Plasma
Supervisors
Therapeutically Targeting Heparan Sulphate To Restore The Endothelial Glycocalyx In Diabetic Microvascular Disease
Supervisors
Adiponectin in the maintenance and protection of glomerular endothelial cells and the glycocalyx in diabetes
Supervisors
Publications
Recent publications
08/03/2023Mineralocorticoid receptor antagonism in diabetes reduces albuminuria by preserving the glomerular endothelial glycocalyx
JCI Insight
Podocyte protease activated receptor 1 stimulation in mice produces focal segmental glomerulosclerosis mirroring human disease signaling events
Kidney International
Epigenetic Mechanisms and Nephrotic Syndrome
Biomedicines
Circulating hyaluronan as a marker of endothelial glycocalyx damage in dogs with myxomatous mitral valve disease and dogs in a hypercoagulable state
Veterinary Journal
Endothelial glycocalyx is damaged in diabetic cardiomyopathy
Diabetologia