Dr Sam Hayward
BMedSci - 1st class honours, MBChB, MRCP
Current positions
Academic Clinical Lecturer
Bristol Medical School
Contact
Press and media
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Research interests
I am a kidney doctor with an interest in genomics and molecular epidemiology. My PhD research focuses on people with Nephrotic syndrome; I am utilising machine learning to interrogate the genetic and epigenetic profiles of people with this kidney disorder to improve our understanding of disease drivers and our ability to predict prognosis.
Projects and supervisions
Research projects
The role of DNA methylation in stratifying and understanding paediatric nephrotic syndrome - a combined bioinformatics and CRISPR-cas9 approach
Principal Investigator
Description
PhD fellowship to investigate epigenetic differences between Nephrotic Syndrome subgroups.Managing organisational unit
Bristol Medical SchoolDates
01/09/2021 to 01/07/2025
The burden of polypharmacy in older people with advanced chronic kidney disease
Role
Co-Investigator
Description
Exploring the prevalence of polypharmacy and the changes in prescribing prior to death in older people with advanced chronic kidney disease.Managing organisational unit
Bristol Medical SchoolDates
01/08/2017 to 22/09/2023
Publications
Selected publications
10/02/2023Epigenetic Mechanisms and Nephrotic Syndrome: A Systematic Review
Biomedicines
What is circulating factor disease and how is it currently explained?
Pediatric Nephrology
International prescribing patterns and polypharmacy in older people with advanced chronic kidney disease: results from the European Quality Study
Nephrology Dialysis Transplantation
Kidney Failure Prediction Models: A Comprehensive External Validation Study in Patients with Advanced CKD
Journal of the American Society of Nephrology
DNA methylation and response to steroids in children with nephrotic syndrome: 57th ERA-EDTA Congress - Nephrology Dialysis Transplantation
57th ERA-EDTA Congress Abstracts
Recent publications
21/01/2025A novel, dominant disease mechanism of distal renal tubular acidosis with specific variants in ATP6V1B1
Nephrology Dialysis Transplantation
Association between glucosamine use and albuminuria in the UK: a cohort and Mendelian Randomisation study
BMJ Open
Cardiometabolic protein expression levels and pathways associated with kidney function decline in older European adults with advanced kidney disease
Clinical Kidney Journal
Quantifying association of early proteinuria and estimated glomerular filtration rate changes with long-term kidney failure in C3 glomerulopathy and immune-complex membranoproliferative glomerulonephritis using the United Kingdom RaDaR Registry
Kidney International
National Unified Renal Translational Research Enterprise: Idiopathic Nephrotic Syndrome (NURTuRE-INS) study
Clinical Kidney Journal
Thesis
The role of DNA methylation in stratifying and understanding nephrotic syndrome
Supervisors
Award date
13/05/2025
Related people
Professor Gavin Welsh
Academic Director (Research Translation & Commercialisation)
Health and Life Sciences Faculty Office
Professor Moin Saleem
Professor
Bristol Medical School
Professor Fergus Caskey
Professor of Renal Medicine
Applied Health Research
Dr Barny Hole
NIHR Academic Clinical Lecturer in Health Needs of Older People: Renal Medicine
Applied Health Research
Dr Kevon Parmesar
Clinical Research Fellow
Bristol Medical School