Dr Matthew Butler
BSc, MBChB, PhD
Current positions
Consultant Senior Lecturer & MRC Clinician Scientist
Bristol Medical School (THS)
Contact
Press and media
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Projects and supervisions
Research projects
Determining The Therapeutic Potential Of Gene Therapy For Translation Of Glycocalyx Protection Strategies In Chronic Kidney Disease
Principal Investigator
Role
Co-Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
13/02/2024 to 12/02/2025
Publications
Recent publications
01/06/2024Adiponectin Reduces Glomerular Endothelial Glycocalyx Disruption and Restores Glomerular Barrier Function in a Mouse Model of Type 2 Diabetes
Diabetes
Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes
Cardiovascular Diabetology
Aldosterone: Essential for Life but Damaging to the Vascular Endothelium
Biomolecules
A small molecule chaperone rescues keratin-8 mediated trafficking of misfolded podocin to correct genetic Nephrotic Syndrome
Kidney International
Mineralocorticoid receptor antagonism in diabetes reduces albuminuria by preserving the glomerular endothelial glycocalyx
JCI Insight
Thesis
Aldosterone-induced endothelial glycocalyx dysfunction, a potential therapeutic target in proteinuria?
Supervisors
Award date
25/09/2018