Dr Monica Gamez
BSc, PhD
Expertise
I am interested in the role of heparan sulphate in the vasculature. More specifically, I am interested in its contribution to the maintenance of vascular permeability and how it can be therapeutically targeted in disease.
Current positions
Senior Research Associate
Bristol Medical School (THS)
Contact
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Biography
Monica Gamez graduated from University of Michigan, Ann Abor in 2011 with a BSc in Microbiology. After her undergraduate degree she worked as a laboratory technician where her work primarily focused on viral life cycles and the pathology involved in infection.
In 2017 Monica began her PhD studies at the University of Bristol in the Bristol Renal group working under the supervision of Dr. Rebecca Foster, where her project focused on the role of heparan sulphate in the glycocalyx. She graduated with a PhD in 2020 and is now a post-doctoral researcher in the Bristol Renal group working with Dr. Rebecca Foster.
In 2017 Monica began her PhD studies at the University of Bristol in the Bristol Renal group working under the supervision of Dr. Rebecca Foster, where her project focused on the role of heparan sulphate in the glycocalyx. She graduated with a PhD in 2020 and is now a post-doctoral researcher in the Bristol Renal group working with Dr. Rebecca Foster.
Publications
Recent publications
01/06/2024Adiponectin Reduces Glomerular Endothelial Glycocalyx Disruption and Restores Glomerular Barrier Function in a Mouse Model of Type 2 Diabetes
Diabetes
Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes
Cardiovascular Diabetology
Mineralocorticoid receptor antagonism in diabetes reduces albuminuria by preserving the glomerular endothelial glycocalyx
JCI Insight
The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147-receptor-mediated signalling
Clinical Science
The SARS-CoV-2 Spike protein alters human cardiac pericyte function and interaction with endothelial cells through a non-infective mechanism involving activation of CD147 receptor signalling.
European Heart Journal
Thesis
Therapeutically Targeting Heparan Sulphate To Restore The Endothelial Glycocalyx In Diabetic Microvascular Disease
Supervisors
Award date
29/09/2020