Addiction research

Research in this area focuses on identifying patterns and consequences of substance use and antisocial behaviour - including both high-risk and population based approaches to the prevention of substance use and antisocial behaviour. 

The key themes are:

Trajectories and consequences - alcohol, tobacco, and cannabis - in adolescents and young people utilising ALSPAC - including the association between cannabis and schizophrenia; trajectories of tobacco use Tobacco and Alcohol Research Group; multiple risk behaviour DECIPHER; and the association between adolescent alcohol use and harm in young adults NIHR School of Public Health Research.

Epidemiology and prevention of consequences of heroin and injecting drug use - including modelling and assessing rick of Hepatitis C, Hepatitis B and HIV (Infection and Immunity); assessing natural history and mortality risk through analysis of Edinburgh Addiction Cohort and record linkage with other administrative cohorts; and Multiple Parameter Evidence Synthesis of drug related crime. 

Our work also contributes to two MRC Addiction Research Clusters.

Selected Publications

    Martin N, Hickman M, Hutchinson S, Goldberg D, Vickerman P. Combination interventions to prevent HCV transmission among people who inject drugs: modelling the impact of antiviral treatment, needle and syringe programmes, and opiate substitution therapy. Clinical Infectious Diseases. 2013 57 Suppl 2:S39-S45
    MacArthur GJ, Minozzi S, Martin NK, Vickerman P, Deren S, Bruneau J, Degenhardt L, Hickman M. Opiate substitution treatment and HIV transmission in people who inject drugs: a systematic review and meta-analysis. BMJ 2012;345:e5945. doi: 10.1136/bmj.e5945
    Heron J, Macleod J, Munafò MR, Melotti R, Lewis G, Tilling K, Hickman M. Patterns of alcohol use in early adolescence predict problem use at age 16. Alcohol Alcohol. 2012;47(2):169-77
    Cornish R, Macleod J, Strang J, Vickerman P, Hickman M Risk of death during and after opiate substitution therapy in primary care: a prospective observational study in the UK General Practice Research Database. BMJ 2010;341:c5475
    Kimber J, Copeland L, Hickman M, Macleod J, McKenzie J, Angelis D, Robertson J. Survival and cessation in injecting opiate users, a prospective observational study of outcomes and the effect of opiate substitute treatment BMJ 2010;341:c3172