Personality disorder
Personality disorder affects 1-in-12 of the adult population. The condition has significant effects on the health of individuals, their life expectancy and their use of services. Research from our Centre has charted the epidemiology of personality disorder, tracked its public health consequences and tested novel interventions designed to help people with the condition. Our research has contributed to clinical guidelines and influenced policy in the field.
The personality disorders research theme spans epidemiological studies and translational research and we use a range of methods including observational studies, randomised controlled trials and mixed methods studies.
Selected Publications
- Moran P, Bick D, Biddle L, Borries B, Kandiyali R, Mgaieth F, Patel V, Rigby J, Seume P, Sadhnani V, Smith N, Swales M, Turner N (2025). Perinatal emotional skills groups for women and birthing people with borderline personality disorder: outcomes from a feasibility randomised controlled trial. BJPsychOpen, 11 (2025), e12 http://dx.doi.org/10.1192/bjo.2024.833
- Moran, P, Chandler A, Dudgeon P et al. (2024). The Lancet Commission on Self-Harm. The Lancet https://doi.org/10.1016/S0140-6736(24)01121-8
- Knipe D, Moran P, Howe L, Karlson S, Kapur N, Revie L, John A. Ethnicity and suicide in England and Wales: A national linked cohort study (2024). Lancet Psychiatry Volume 11, Issue 8, 611 – 619 https://doi.org/10.1016/S2215-0366(24)00184-6
- Gajwani R, Sim F, McAllister K, Smith H, McIntosh E, Moran P, Ougrin D, Smith M, Gumle A, Chanen A, Minnis H (2024). The BRIDGE project: a feasibility randomised controlled trial of brief, intensive assessment and integrated formulation for young people (age 14-24) with features of borderline personality disorder (Protocol) Psychiatry, 24 September 2024 Sec. Adolescent and Young Adult Psychiatry. Volume 15 - 2024 https://doi.org/10.3389/fpsyt.2024.1389578
- Warbrick, L.A., Dunn, B.D., Moran, P.A.et al. (2023). Non-randomised feasibility study of training workshops for Talking Therapies service high-intensity therapists to optimise depression and anxiety outcomes for individuals with co-morbid personality difficulties: a study protocol. Pilot Feasibility Stud 9, 170 https://doi.org/10.1186/s40814-023-01394-z
- Padmanathan P, Cohen R, Gunnell D, Biddle L, Griffith E, Breheny K, Hickman M, Munien N, Patel A, Crocker E, Moran P. Development of a brief intervention for Emergency Department attendees presenting with self-harm and co-occurring substance use problems: a Delphi method study. Crisis: The Journal of Crisis Intervention and Suicide Prevention 45(4), 254–262. https://doi.org/10.1027/0227-5910/a000933
Fonagy P, Simes E, Yirmiya K, Wason J, Barrett B,Frater A, Cameron A, Butler S, Hoare Z, McMurran M, Moran P, Crawford M, Pilling S, Allison E, Yakeley J, Bateman A (2025). Mentalization-based treatment for antisocial personality disorder in male offenders on community probation in England and Wales (Mentalizing for Offending Adult Males, MOAM): a randomised controlled trial. Lancet Psychiatry.
Robson EM, Husin HM, Vijayakumar N, Dashti SG, Moreno-Betancur M, Moran P, Patton GC, Sawyer SM (2025). The course of common mental disorders across adolescence: the Child to Adult Transition Study (CATS). Lancet Psychiatry Jan;12(1):44-53. doi: 10.1016/S2215-0366(24)00361-4. Epub 2024 Dec 4.
Hodsoll J, Strawbridge R, King S, Taylor R, Breen G, Grant N, Grey N, Hepgul N, Hotopf M, Kitsune V, Moran P, Tylee A, Wingrove J, Young A, Cleare A (2024). Predictors of outcome following psychological therapy for depression and anxiety in an urban primary care service: a naturalistic Bayesian prediction modeling approach.Psychological Medicine. 54(16):4503-4517. doi:10.1017/S0033291724001582
Vamvakas G,Jarrett M, Barrett B, Campbell C, Forrester A, Trebilcock J, Walker J, Weaver T, Khondoker M & Moran P (2024) The effectiveness of the offender personality disorder pathway: a propensity score-matched analysis, Psychology, Crime & Law, DOI: 1080/1068316X.2024.2310532