The Dementia Research Group conducts preclinical and clinical research in dementia. We use molecular genetic, biochemical, cell culture-based and neuropathological approaches, as well as cognitive and neuroimaging studies in patients. Our aim is to translate our preclinical findings into applications that benefit patients with dementia. At the heart of this is our focus on the molecular epidemiology and pathogenesis of Alzheimer's disease and related dementias.
Our clinical research is based in the BRACE Centre and our preclinical research is based in the John James Laboratories at Frenchay Hospital. The John James Laboratories also house the Human Tissue Authority-licensed South West Dementia Brain Bank.