Actin Rearrangement

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3D reconstruction illustrating actin rearrangement induced by Salmonella infecting Madin-Darby canine kidney (MDCK) cells. TRITC-phalloidin (red) reveals F-actin reorganisation into structures resembling membrane ruffles while FITC-labelled antibodies locate invading Salmonella. Confocal images obtained with a Leica TCS SP system and 3D rendering performed with Leica confocal software.

Alan Leard and Mark Jepson, Cell Imaging Facility

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