The subject scored 93% against measures which included teaching quality, research quality and student experience.
A number of other disciplines at Bristol were also ranked in the top 5, including Civil and General Engineering, Music, German, Dentistry, Education, and French.
Overall, the Guide ranked the University of Bristol within the top 10 universities in the UK.
The Guide noted that “the combination of a leading research university and a charming cosmopolitan city that’s within easy reach of most of the country makes Bristol one of the most consistently popular destinations for students.”
Professor Evelyn Welch, Vice-Chancellor and President of the University of Bristol, said: “We are proud to be recognised for our unwavering commitment to delivering world-class education and research in an exciting, vibrant city like Bristol.
“Our rise into the UK’s top 10 is a testament to the dedication of our staff and students, and to our ambition to lead globally through innovation, collaboration, and academic excellence.”