Bristol Medical School

£1.8 million for trial to evaluate treatment for chronic severe low back pain

Researchers at the University of Bristol, in collaboration with North Bristol NHS Trust, the Universities of Keele and Southampton have been awarded £1.8 million from the National Institute of Health Research (NIHR) to evaluate a treatment for chronic severe low back pain. Led by Dr Vikki Wylde, the RADICAL study will be a randomised controlled trial to find out if radiofrequency denervation, a procedure commonly used in the NHS, can provide pain relief.

Scientists reveal how a faulty gene leads to kidney disease

New insights into why a faulty gene involved in a devastating form of a kidney condition called nephrotic syndrome leads to disease in some patients have been identified in new Kidney Research UK-funded research led by the University of Bristol. The findings, published in the Journal of the American Society of Nephrology (JASN), could pave the way for new ways to prevent or treat the condition, by revealing new targets to intervene in the process. Around 1 in 50,000 children are diagnosed with nephrotic syndrome each year.