Approved Research Proposals
The following table displays all research proposals that have been approved by The Cleft Collective Project Management Group (PMG). If you would like to submit a research proposal to the PMG please visit Accessing the Resource to find out how.
| Project Number | Project Title | PI & Affiliation | Approval Date |
|---|---|---|---|
| CC071 | Multi-ancestry GWAS meta-analysis of non-syndromic orofacial cleft | Z Jia, Exeter University & Sichuan University | January 2025 |
| CC067 | Assessing if Maternal Exposure During Pregnancy Affects the Severity of Cleft Palate (+/- Lip) | J Kennedy, University of Bristol | December 2024 |
| CC066 | Van der Woude unilateral cleft lip: a new definition in severity | W Breakey, Royal Children’s Hospital Melbourne & Birmingham Children’s Hospital | December 2024 |
| CC064 | Current surgical practices in the UK for primary nasal correction in children born with cleft lip and/or palate. | N Narayan, University Hospitals Bristol and Weston | July 2024 |
| CC063 | Relationship between Intelligibility in Context Scale and Cleft Speech Characteristics in 3-years-olds with a Cleft (Lip and) Palate |
C Alighieri, University of Ghent | July 2024 |
| CC062 | Separating out genetic and non-genetic factors for educational and behavioural outcomes in children born with a cleft using genome wide study data. | S Lewis, University of Bristol | March 2025 |
| CC061 | Does the management of the tensor aponeurosis during primary palatoplasty affect eustachian tube function and hearing outcomes? | S Gholami, Newcastle University | April 2024 |
| CC060 | Developing reference data for the Intelligibility in Context Scale and exploring associations between intelligibility and language development for 5-year-old children born with cleft lip and/or palate | Y Wren, University of Bristol | March 2024 |
| CC058 | A longitudinal study monitoring the effect of different types of cleft lip and palate on growth parameters at birth and 18 months. | J Nagpal, University of Bristol | February 2024 |
| CC057 | Exploratory study to investigate the impact of sleep behaviour on language development in children with cleft lip and palate. | S van Eeden, Newcastle University | December 2023 |
| CC056 | Is there a relationship between expressive language skills at 18/ 24 months and cleft speech characteristics at 36 months? | R Pinkey, Cardiff Met | December 2023 |
| CC055 | Does infant feeding habits in children with Pierre Robin sequence influence dental health? | F Gilchrist, University of Sheffield | December 2023 |
| CC054 | Influence of maternal diet on cleft type | S van Eeden, Alderhey Children's Hospital | September 2023 |
| CC053 | Investigating treatment pathways for wide cleft palate | N Narayan, The University of Bristol | September 2023 |
| CC052 | Mother’s health and medication use during pregnancy and orofacial cleft | A Christou, The University of Bristol | March 2023 |
| CC051 | Is there an association between maternal and paternal alcohol consumption in the risk of cleft? | M Hart, The University of Bristol | March 2023 |
| CC050 | Understanding the impact of the COVID-19 pandemic on speech and language development in children born with a cleft. | L Southby, The University of Bristol | February 2023 |
| CC049 | Exploring the prevalence of Faltering weight in Cleft lip and palate | Nitisha Narayan, The University of Bristol | January 2023 |
| CC048 | Improving mental health outcomes in children born with an orofacial cleft: Identifying children at most risk to target clinical provision | E Stergiakouli, The University of Bristol | September 2022 |
| CC047 | Are there anatomic factors in the first year of life that influence speech outcomes for children with cleft palate at age 3 and 5 | K Mason, Wyoming University | July 2022 |
| CC046 | Dental care pathways and parent reported experiences and outcomes for 5-year-old children with cleft in the UK | S Simon, The University of Bristol | May 2022 |
| CC045 |
Patterns of speech sounds after surgery: investigating infants’ phonological development following full cleft palate restorative surgery |
A Langer, Cardiff University | April 2022 |
| CC043 |
Early language indicators and their relationship with Speech and Language Therapists ability to judge velopharyngeal function in children born with cleft palate at age 18-24 months |
H Chandler, Cambridge University Hospitals NHS Foundation Trust | December 2021 |
| CC042 | Left vs right sided clefts – is there a difference in outcomes? | M Al-Hassini, The University of Bristol | November 2021 |
| CC041 | Caries in Cleft | A Gormley, The University of Bristol | November 2021 |
| CC040 | Longitudinal assessment of parental psychological wellbeing and its influence on child outcomes in cleft lip/palate | N Stock, The University of the West of England | November 2021 |
| CC038 | Describing the prevalence of other developmental anomalies and family history among children born with a cleft in the UK | V Saxena, The University of Bristol | June 2021 |
| CC037 | Validating preoperative cleft palate measurements from the Surgical Form | A Davies, The University of Bristol | April 2021 |
| CC036 | Associated syndromes with Pierre Robin sequence | A Davies, The University of Bristol | April 2021 |
| CC035 | Does the use of perioperative antibiotics at the time of cleft palate repair affect the rate of postoperative fistula? | A Davies, The University of Bristol | April 2021 |
| CC034 | Parental perceptions regarding dental concerns for cleft patients: A National Study | P Sinnott, Bristol Dental Hospital | April 2021 |
| CC033 | Does consonant inventory at 18/24 months predict speech outcomes at 36 months in children with non-syndromic CL/P? | J Boyce, Melbourne University | January 2021 |
| CC032 | The impact of parental wellbeing on early speech, language and communication development for children born with cleft palate and/or lip. | C Wiliams, Newcastle University | November 2020 |
| CC031 | How are the early language skills of children with Cleft Lip and/or Palate assessed, and are these measures adequate? | S van Eeden, Newcastle University | November 2020 |
| CC030 | The impact of Covid-19 on children born with a cleft in the UK | The Cleft Collective, The University of Bristol | September 2020 |
| CC029 | Anonymised summary report of patient responses to the Cleft Collective Covid-19 questionnaire | Multiple Cleft Teams, United Kingdom | September 2020 |
| CC028 | Exploring Prenatal Influences on Child Health (EPoCH) | G Sharp, The University of Bristol | September 2020 |
| CC027 | The influence of family socioeconomic position and race on the healthcare and outcomes of children born with orofacial clefts | G Sharp, The University of Bristol | September 2020 |
| CC026 | Assessing the listening skills of children with cleft lip and palate: a study using the Evaluation of Children’s Listening and Processing Skills (ECLiPS) questionnaire. | S van Eeden, Newcastle University | August 2020 |
| CC025CC025 | Exploring relationships between children’s cleft type and their birth outcomes | Q Yang, The University of Bristol | June 2020 |
| CC024 | Triangulating evidence from multiple control groups to study the causes and consequences of being born with cleft lip/palate | C Moore, The University of Bristol | April 2020 |
| CC023 | Consonant inventories of children born with cleft palate at the age of 18-24 months in the UK | H Ayyad, Kuwait University | March 2020 |
| CC022 | Do infants born with cleft palate and Robin Sequence (RS) exhibit fewer communication behaviours compared to those with isolated cleft palate (ICP)? | S Van Eeden, Newcastle University | March 2020 |
| CC021 | Validation of the cleft phenotype in the Cleft Collective | A Davies, The University of Bristol | January 2020 |
| CC020 | Early communication skills in children born with cleft palate with or without cleft lip | H Lane, Doncaster & Bassetlaw Hospitals NHS Foundation Trust | January 2020 |
| CC019 |
A review of the utilisation of the Cleft Lip and Palate Association (CLAPA)’s services by the cleft community |
K Ardouin, Cleft Lip and Palate Association | October 2019 |
| CC018 |
Do early communication behaviours of infants born with cleft palate vary by cleft subtypes? |
H Perryer, Bristol Speech & Language Therapy Research Unit and West Midlands Cleft Lip & Palate Sevice | May 2019 |
| CC017 |
Evaluating the psychological wellbeing and behavioural development of children with cleft lip and/or palate at age 5 and 8 |
S Berman, The University of Bristol | May 2019 |
| CC016 | Exploring the relationship between palatal cleft type and width and the use of relieving incisions | A Davies, South West Cleft Service, Bristol Dental Hospital | January 2019 |
| CC015 | Exploring current trends in cleft surgery across the UK | M Fell, North Bristol NHS Trust | January 2019 |
| CC013 | A genome wide association (GWAS) study of cleft with stratification by cleft subtype. | S Lewis, The University of Bristol | November 2018 |
| CC012 | Hypothesis-driven and hypothesis-free Mendelian randomization analyses to identify potentially modifiable risk factors for cleft and cleft-related outcomes | S Lewis, The University of Bristol | November 2018 |
| CC011 | A genome wide association study of mums of children born with a cleft | S Lewis, The University of Bristol | November 2018 |
| CC010 | Is there a relationship between hearing loss and cleft speech characteristics in children born with cleft palate? | S Baker, Cardiff Metropolitan University | October 2018 |
| CC009 | Exploring relationships and associations between children’s cleft type and early speech and language development |
Y Wren, Bristol Speech and Language Therapy Unit, North Bristol NHS Trust |
September 2018 |
| CC008 | Parental psychological adjustment following a diagnosis of cleft lip and/or palate and associated risk factors | N Stock, The University of the West of England | July 2017 |
| CC007 | Satisfaction with healthcare among parents of children born with cleft lip and/or palate | N Stock, The University of the West of England |
July 2017 |
| CC006 |
Understanding speech processing abilities and their relationship to PSD in children born with cleft palate. (The SPARC study) |
L Southby, The University of Bristol (hosted by Oxford Health NHS Foundation Trust) | May 2017 |
| CC005 | Cognitive, social and emotional development among children born with cleft lip and/or palate at 18 months | N Stock, The University of the West of England | May 2017 |
| CC004 | Families’ Views on Anaesthesia and Surgery for Repair of Oral Cleft: A Qualitative Analysis of a Focus-group Discussion | H Gill, University of Bristol |
March 2017 |
| CC003 | What is the impact of cleft lip/palate on families' quality of life, and how might healthcare and support be improved? | N Stock, The University of the West of England | November 2016 |
| CC002 | DNA methylation in blood and tissue of children with cleft lip/palate | G Sharp, University of Bristol | August 2016 |
| CC001 | Cellular characterisation of the human cleft palate with clinical correlation | J Hardwicke, University of Birmingham | March 2014 |