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Independent analysis finds the Oxford COVID-19 vaccine follows its programmed genetic instructions 23 October 2020 The AstraZeneca Oxford COVID-19 vaccine (ChAdOx1 nCoV-19 and also known as AZD1222) now undergoing Phase III clinical trials, has already undergone rigorous testing to ensure the highest standards of quality and safety. Now a team at the School of Cellular and Molecular Medicine, Bristol University has used recently developed techniques to further validate that the vaccine accurately follows the genetic instructions programmed into it by the Oxford team. This novel analysis provides even greater clarity and detail about how the vaccine successfully provokes a strong immune response.
  • Independent analysis finds the Oxford COVID-19 vaccine follows its programmed genetic instructions 23 October 2020 The AstraZeneca Oxford COVID-19 vaccine (ChAdOx1 nCoV-19 and also known as AZD1222) now undergoing Phase III clinical trials, has already undergone rigorous testing to ensure the highest standards of quality and safety. Now a team at the School of Cellular and Molecular Medicine, Bristol University has used recently developed techniques to further validate that the vaccine accurately follows the genetic instructions programmed into it by the Oxford team. This novel analysis provides even greater clarity and detail about how the vaccine successfully provokes a strong immune response.
  • Neuropilin-1 drives SARS-CoV-2 infectivity, finds breakthrough study 21 October 2020 In a major breakthrough an international team of scientists, led by the University of Bristol, has potentially identified what makes SARS-CoV-2 highly infectious and able to spread rapidly in human cells. The findings, published in Science on 20 October describe how the virus’s ability to infect human cells can be reduced by inhibitors that block a newly discovered interaction between virus and host, demonstrating a potential anti-viral treatment.
  • Bristol is part of new £4 million FDA study to advance understanding of severe coronavirus infection 7 October 2020 Bristol is part of a major new international project to improve our understanding of severe coronavirus infection in humans. The study, funded by the US Food and Drug Administration (FDA), will analyse samples from humans and animals to create profiles of various coronaviruses, including SARS-CoV-2, which causes COVID-19. The results will help inform the development of new treatments and vaccines to tackle coronavirus infections.
  • Discovery of a druggable pocket in the SARS-CoV-2 Spike protein could stop virus in its tracks 23 September 2020 A druggable pocket in the SARS-CoV-2 Spike protein that could be used to stop the virus from infecting human cells has been discovered by an international team of scientists led by the University of Bristol. The researchers say their findings, published today [21 September] in the journal Science, are a potential 'game changer' in defeating the current pandemic and add that small molecule anti-viral drugs developed to target the pocket they discovered could help eliminate COVID-19.
  • Researchers extend recruitment to COVID-19 vaccine trial 21 August 2020 Researchers at University Hospitals Bristol and Weston NHS Foundation Trust (UHBW), North Bristol NHS Trust (NBT) and the University of Bristol have begun a new round of recruitment to a clinical trial of a vaccine pioneered in the UK which could protect against COVID-19.
  • Trailblazing study discovers novel genetic causes of rare diseases, leading to improved diagnosis and better patient care 3 July 2020 A research programme pioneering the use of whole genome sequencing in the NHS has diagnosed hundreds of patients and discovered new genetic causes of disease.
  • Vital coronavirus research to track frontline NHS staff in Bristol 8 May 2020 Healthy frontline NHS staff in Bristol will be studied as part of a ground-breaking research project led by infectious disease and immunology specialists from Bristol Royal Hospital for Children and the University of Bristol.
  • Research into Covid-19 - Bristol Research: Digital Fireside Talks 28 April 2020 The University's Pro Vice Chancellor (Health and Life Sciences) Professor John Iredale talks to Professor Adam Finn, Professor of Paediatrics in the first episode of YouTube talks about the University's research response to Covid-19.
  • Dramatic increase in bowel cancer in young adults in England 10 March 2020 There has been a dramatic increase in the incidence of bowel cancer in adults under the age of 50, according to new research from the University of Bristol, UWE Bristol and University Hospitals Bristol NHS Foundation Trust (UH Bristol).
  • Stephanie Diezmann: Celebrating Life in Science 6 March 2020 Drinalda Cela, a PhD student in CMM, interviewed Dr Stephanie Diezmann about her research, inspiration and life in science.
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