TRAC-facilities, services and equipment

The University has a number of high-spec, state-of-the-art facilities that are technically supported and available for use by external researchers and industry, search the list below for services or equipment.

If Bristol does not offer the service you require, try the wider regional Universities community - the GW4 partnership

NameServicesContactCategoriesEquipment
Animal Behaviour Clinic
  • Behaviour consultation
  • Referring clinical cases
  • Residency programme
  • Separation related behaviours

Clinical Behaviour Office

Langford-behaviour@bristol.ac.uk

Veterinary Services, Animal welfare  
Biological NMR Facility
  • High-field Nuclear Magnetic Resonance spectrometry
  • Protein and small molecule structure analysis
  • Protein-ligand binding studies

Matt Crump

Matt.Crump@bristol.ac.uk

NMR spectrometry  
Bristol Genomics Facility
  • DNA and RNA sequencing
  • Microarray expression analysis
  • High-throughput Genotyping
  • Real-time quantitative PCR
  • Capillary sequencing and genotyping
  • DNA and RNA analysis and quality assessment
  • Bioinformatic support

Jane Coghill or Christy Waterfall

genomics-facility@bristol.ac.uk

DNA and RNA analysis

Illumina NextSeq 500, Illumina MiSeq,  Affymetrix GeneTitan MC- instrument (high throughput), Affymetrix GeneChip Scanner (low throughput), Nanodrop ND-8000, Nanodrop ND-1000, Agilent TapeStation 2200, Invitrogen Qubit fluorimeter , Diagenode Bioruptor sonicator, Roche LightCycler 480, Applied Biosystems 3500 capillary electrophoresis sequencer

 

Bristol University NanoESCA Laboratory (BrUNEL)
  • High-resolution surface chemical state analysis
  • PEEM, SPA-LEED, XPS
  • Imaging and spectroscopy/diffraction modes
  • Specialist light sources
  • In situ annealing and sputtering
  • UHV suitcase

Neil Fox

info-nanoesca@bristol.ac.uk

Surface analysis, imaging, materials analysis, electron diffraction, spectroscopy

Scienta Omicron NanoESCA II, multichannel XPS, monochromated x-ray source, LEED, low energy electron diffration, PEEM, photoemission electron microscopy, UHV suitcase

 

Centre for Nanoscience and Quantum Information (NSQI)
  • Low and ultra low vibration research spaces
  • Soundproof chamber
  • Technically supported

Steve Neck

Steve.Neck@bristol.ac.uk

Low vibration space

purpose built low noise and ultra-low noise labs: set in the basement, these labs achieve vibration levels lower than the lowest recognised criteria (Vibration Criteria G – VC-G). As well as anti-vibration measures, the labs are also protected from electrical noise, Mixed lab space, a sound proof chamber, class 1000 clean room, two sample preparation labs, tissue culture room
Chemical Imaging Facility
  • SEM, TEM and AFM
  • Nanoscale imaging and analysis
  • Full technical and training support

Sean Davis  

S.A.Davis@bristol.ac.uk 

Imaging, analysis, electron microscopy, atomic force microscopy

JEOL 200 Kv Field Emission Gun TEM 2100F with STEM, electron diffraction, Gatan digital camera, Oxford Instruments Energy Dispersive X-ray analysis system (80mm2 SSD; Aztec). Gatan Cryo holder and heating holder.
JEOL 120 Kv 1400 TEM with Gatan digital camera
JEOL 120 Kv 1200 Mk2 TEM with SIS digital camera
JEOL SEM IT300 LV with Oxford Instruments Energy Dispersive X-ray analysis system (80mm2 SSD; Aztec)
JEOL Field Emission Gun SEM 6330 with Gatan Cathodoluminescence and Oxford Instruments Energy Dispersive X-ray analysis
Bruker Multimode 3 with Quadrexed Nanoscope 3D controller
Bruker Multimode 8 PeakForce QNM allowing conductivity and quantitative material property (including modulus, adhesion, deformation, and dissipation) mapping.
Vacuum coating (C and Pt/Pd, Au)
Ultramicrotomy
Critical point drying and freeze-drying

Chemical Mass Spectrometry Facility
  • HPLC-MS/UPLC-MS
  • LC-MSn
  • Nano-LC-MS
  • IMS-MS
  • Accurate mass, EI, CI, ESI, nanospray and Maldi MS

Paul Gates

Paul.Gates@bristol.ac.uk

Mass spectrometry, material analysis  

Thermo Scientific Orbitrap Elite High resolution (MSn) mass spectrometer with UPLC/HPLC.

Waters Synapt G2S IMS-TOF mass spectrometer with Nanomate source.

Bruker Daltonics UltrafleXtreme 2 High resolution MALDI-TOF/TOF mass spectrometer.

Bruker Daltonics micrOTOF Focus II High resolution TOF mass spectrometer.

Applied Biosystems 4700 Proteomics MALDI-TOF/TOF mass spectrometer.

Bruker Daltonics Esquire 6000 Ion-trap mass spectrometer with HPLC.

VG Autospec 3 sector (double focussing) mass spectrometer 

Chemical NMR Facility
  • Solution state Nuclear Magnetic Resonance spectrometry of small molecules
  • Multinuclear and diffusion NMR
  • Molecular structure and mixture analysis

Craig Butts

Craig.Butts@bristol.ac.uk

NMR spectrometry

 

Bruker 700 MHz spectrometer with 1.7 mm cryoprobe

Bruker Avance 400

Bruker Avance 300

Bruker 500 MR NMR Spectromer  with 13C cryoprobe

JEOL Eclipse 300 NMR Spectrometer

JEOL ECS 400 NMR Spectrometer

JEOL ECS 300 NMR Spectrometer

Varian 400 MR NMR Spectrometer

Varian 500 VNMRS NMR Spectrometer

Varian INOVA 600 MHz NMR Spectrometer

Varian VNMRS 600 spectrometer with cryoprobe 

Electron Microbeam Laboratories
  • Nanoscale imaging and quantitative compositional analysis
  • Training in Electron Microscopy and X-ray microanalysis methods

Stuart Kearns

Stuart.Kearns@bristol.ac.uk

Imaging, materials analysis, electron microscopy, spectropscopy

 

Scanning Electron Microscopy, Electronprobe Microanalysis, Hitachi S-3500N variable pressure microscope equipped with Thermo Noran energy dispersive spectrometer (EDS x-ray detector), environmental secondary electron detector (ESED) and BSE detector, JEOL JXA8530F Hyperprobe (EPMA), Field Emission Gun electron source, Cameca SX100 microprobe, 5 wavelength dispersive spectrometers and 1 energy dispersive spectrometer.
Histology Services
  • Fresh and fixed, frozen sectioning
  • Fixation and staining
  • Wax processing
  • Immunocytochemistry
  • Immunofluoresent staining
  • Image capture
  • Consultancy

Debbie Martin

debbie.martin@bristol.ac.uk

Clinical studies, Histology, Histochemistry

 

Dedicated facility.
Cryostat x4.
Sliding microtome with peltier cooling x1.
Rotary microtomes x4.
Thermo Excelsior processor.
Medite TP15 processor.
Medite embedding centre.
Slide printer.
Cassette printer.
Leica DM750 microscope with integral digital camera.
Motik SMZ-168 dissecting microscope with integral digital camera with bespoke thermal stage for orientation of wax embedded tissue.
Vast range of stains.
10L Liquid nitrogen dewar.
Virtual Microscope.
Shandon knife sharpener.

ICP-OES service
  • Inductively Coupled Plasma – Optical Emission Spectrometry
  • Trace analysis of aqueous solutions
  • Metal, CA, Na and K ion detection
  • Soil leachate analysis

Chung Choi

P.C.Choi@bristol.ac.uk

Analysis, spectroscopy Agilent 710 ICP-OES, Inductively Coupled Plasma Optical Emission Spectrometer
Illumina Facility
  • Illumina microarray processing and expertise
  • Methylation analysis
  • SNP genotyping arrays
  • Bioinformatics support
  • Dedicated Biobank storage facility

Wendy McArdle

bbl-arrays@bristol.ac.uk

DNA analysis, Genotyping Illumina iscan, autoloader and array processing robot
Interface Analysis Centre (IAC)
  • Materials analysis
  • Focused Ion Beam (FIB)
  • Electron and Optical microscopy
  • Spectroscopy
  • X-ray diffraction
  • Thermogravimetric Calorimetry (DSC)

Keith Hallam

k.r.hallam@bristol.ac.uk

Imaging, materials analysis, electron microscopy, spectroscopy, optical microscopy

Quantachrome Nova 1200, Combined Focussed Ion Beam and Electron Microscopy, FEI Helios NanoLab 600 with three-axis micromanipulator, Oxford Instruments X-Max50 EDX and force measurement system
Focussed Ion Beam, FEI FIB201 with ex-situ TEM lift-out workstation, High-Speed Atomic Force Microscopy, University of Bristol custom-built, world’s fastest, areas 100s of µm in size, resolution down to 2nm
Optical Microscopy and Image Analysis, Leica GZ6 stereo zoom optical microscope, Nikon Metaphot compound optical microscope, Olympus BH2 compound optical microscope with colour CCD camera and computer for image acquisition
Olympus BX60 compound optical microscope with CCD camera and computer for image acquisition, Olympus SZ11 stereo zoom optical microscope with colour CCD camera and computer for image acquisition
Raman Spectroscopy, Renishaw System 2000 microRaman imaging spectrometer, 632.8nm red/514nm green lasers, with integral Leica compound optical microscope
Scanning Electron Microscopy, Zeiss MA10 LaB6 SEM with PGT EDX, backscattered electron detector, large sample chamber, motorised stage, RT-800C hot stage and TSL EBSD system
Zeiss Sigma VP FEG-SEM with Edax coincident EDX/EBSD, backscattered electron detector, large sample chamber, motorised stage and Omicron argon ion gun
Secondary Ion Mass Spectrometry, IAC magnetic sector SIMS/ion milling instrument, Thermogravimetric Analysis/Differential Scanning Calorimetry, Mettler Toledo TGA/DSC1
X-Ray Photoelectron Spectroscopy, Kratos Axis HS XPS with argon ion gun, monochromated x-ray source, dual anode x-ray source,
X-Ray Tomography, associated sample preparation facilities, including cutting, grinding, polishing and coating

Langford Veterinary Services
  • Diagnostic Laboratories
  • Farm Animal Practice
  • Small Animal Hospital
  • Stables Equine Practice

01934 852 650
(Farm Animal Practice)

0117 394 0513
(Small Animal Hospital)

01749 830666
(Stables Equine Practice)

Veterinary services, Animal welfare Outpatient Services, Behaviour, Cardiorespiratory Service, Dermatology, Emergency and Critical Care Unit, Feline Centre, Imaging, Internal Medicine, Neurology / Neurosurgery, Orthopaedics, Pain Management and Anaesthesia, Physiotherapy and Hydrotherapy, Radioactive Iodine, Screening Unit, Soft Tissue Surgery, Dentistry, Gastroenterology, Diagnostic Imaging (MRI, CT scans, X-ray), Neonatology, Neurology and Headshakers, Orthopaedics, Pain Management and Anaesthesia, Poor Performance, Soft Tissue Surgery, Beef Farmers, Camelid Farmers, Consultancy, Dairy Farmers, Pig Farmers, Sheep and Goat Farmers, Smallholders, Youngstock, Cat-Friendly Clinics, Home Visits, Hydrotherapy and Physiotherapy, Interactive Symptom Checker, Nurse Clinics, Pet Drop-Off Service, Puppies and Kittens, Rabbits, Small Furries and Exotic Pets, Surgery and Orthopaedics, X-Ray, CT, MRI and Ultrasound, MDU – PCR and Acarus, Cytology, Profiles and Screens, Biochemistry-Endocrine, Haematology, Histopathology, Meat Spoilage, Microbiology, Virology-Serology
MRC Integrative Epidemiology Unit Metabolomics NMR Facility
  • Quantitative, high-throughput metabolic profiling of human serum/EDTA-plasma
  • Metabolite profiling

Matt Goodwin

matt.goodwin@bristol.ac.uk

Metabolomics

Janus loquid handling robot
Bruker 500MHz NMR Spectrometer
Bruker 600MHz NMR Spectrometer

Mycoplasma Testing Service
  • Cell Line Authentication
  • Repository Production
  • Over Passaging of Cells
  • Cross Contamination
  • Infection Identification and Control
  • Quarantine

Sue Christie

sue.christie@bristol.ac.uk

Clinical Studies, Cell culture  
Proteomics Facility
  • Protein Separation
  • Protein identification
  • Quantitative Proteomics (SILAC, TMT)
  • Phosphoproteomics
  • Serum Proteomics
  • LC-MS service

Kate Heesom

k.heesom@bristol.ac.uk

Proteomics

Orbitrap Fusion Tribrid Mass Spectrometer with up-stream Ultimate 3000 nano-LC system (Thermo Scientific).
LTQ-Orbitrap Velos Mass Spectrometer with up-stream Ultimate 3000 nano-LC system (Thermo Scientific).
DigestPro automated digestion unit (Intavis Ltd.)
2 x Ultimate 3000 stand alone LC systems for peptide fractionation (Thermo Scientific).
GE Healthcare IPGphor3 Isoelectric Focussing Units.
GE Healthcare Ettan DALT Twelve and Six Separation Units.
GE Healthcare DALT Twelve Gel caster.
GE Healthcare Typhoon 9400 Variable Mode Imager.

Science Faculty Workshop
  • Mechanical, glass and electrical engineering
  • Design, prototyping, manufacture, modification, repair and testing

Peter Dunton

p.dunton@bristol.ac.uk

Design, manufacturing, testing SMD re-work station, Water jet cutting, CNC milling, Manual milling and turning, Comprehensive fabrication facilities, including laser, MIG/TIG and MMA welding, traditional hot glass manufacturing equipment, glass diamond saws and grinders. High and ultra-low vacuum, Cryogenics, Laser and optical rigs, AFM and electron microscopy, X-Ray techniques, Medical, veterinary and clinical research
Wolfson Bioimaging Facility
  • Latest-state-of-the-art Light and Electron Microscopy
  • Cell and life sciences imaging for biological and biomedical research

Mark Jepson

m.a.jepson@bristol.ac.uk

Imaging, electron microscopy, optical microscopy

Leica SP5 confocal imaging systems (3, incl 1 with resonant scanner and hybrid detectors)
2 Leica SP8 confocal systems (with resonant scanner and hybrid detectors)
Leica SPE confocal system
Ultraview Spinning Disk
Widefield imaging systems (6, various specs)
Leica TIRF microscope
Leica SP8 Multiphoton
Leica SP8 Fluorescence lifetime imaging microscope
Leica SP8 STED (super-resolution)
Leica SP8 fluorescence correlation spectroscopy
Perkin Elmer Opera LX high content screening system
Essen IncuCyte high throughput live cell imaging system
Tecnai 12 -FEI 120kV BioTwin Transmission Electron Microscope (TEM)
Tecnai 20 -FEI 200kV LaB6 Twin Lens Transmission Electron Microscope (TEM) including HAADF-STEM detector and cryo capabilities
Quanta 400FEI FEG Scanning Electron Microscope (SEM) with cryo attachment
Vitrobot
High Pressure Freezer, Leica EMPACT2 + RTS
Cryo-ultramicrotome
Ultramicrotome
Photo-oxidation light microscope (Correlative Microscopy)
Cryo fluorescence Light Microscope (Correlative Microscopy) 

X-ray Diffraction Facility
  • Single crystal X-ray structure determination (90-400K)
  • Absolute structure determination
  • Routine powder X-ray diffraction measurements
  • Variable temperature powder X-ray diffraction measurements (16-300K)

Hazel Sparkes

hazel.sparkes@bristol.ac.uk

X-ray diffraction, structure determination, single crystal analysis, powder X-ray diffraction  

Bruker D8 Advance Diffractometer Powder diffractometer

Bruker Microstar Rotating Anode Copper Diffractometer

Bruker Kappa Apex II Molybdenum sealed tube single crystal diffractometer 

X-ray Tomography
  • Micro-CT X-ray imaging
  • 3D imaging and analysis
  • Imaging suite workstations and software for 3D visualisation and analysis

Liz Martin-Silverstone

liz.martin@bristol.ac.uk

3D imaging, X-ray tomography  

Nikon XT H 225 ST CT scanner

Imaging lab with high spec workstations and software for 3D visualisation and analysis of tomographic datasets

To add, remove or modify entries, email uob-facilities-feedback@bristol.ac.uk with the details.

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