Postgraduate research projects: Translational Health Sciences

Project titleSupervisorsResearch group
How does the one-humped Arabian camel survive in the desert without drinking?

Prof David Murphy, Dr Michael Greenwood

Laboratories for Integrative Neuroscience and Endocrinology
Experimental and computational modelling of hippocampal neurogenesis and neuronal maturation using human induced pluripotent cells Dr D Atan, Professor K Tsaneva-Atanasova Opthalmology
Elucidating the importance of PPAR signalling in the podocyte in the development of diabetic kidney disease. Professor Richard Coward, Dr Gavin Welsh Bristol Renal
Exploring the pathophysiological role of pericytes in Alzheimer's disease Dr S Miners, Professor S Love  Institute of Clinical Neuroscience
Regulation of arterial remodelling by Wnt proteins as result of hypertension Prof Sarah George, Dr Jason Johnson Bristol CardioVascular
The role of the IGF axis in bladder cancer progression Dr Claire Perks, Jeff Holly, Anthony Koupparis and Amit Bahl IGFs and Metabolic Endocrinology Group 
Can changes in lifestyle that modify the immune system slow the progression of prostate cancer? Jeff Holly, Claire Perks, Amit Bahl, Nic Timpson IGFs and Metabolic Endocrinology Group
The emerging role of RAS in Alzheimer’s disease and dementia Professor Patrick Kehoe, Dr Scott Miners Institute of Clinical Neuroscience
Understanding the role of the novel apelin receptor ligand Apela in the regulation of neuroendocrine function Dr Anne-Marie O’Carroll, Dr Stephen Lolait Laboratories for Integrative Neuroscience and Endocrinology
Microfabrication and in vivo testing of small-diameter tissue-engineered vascular grafts Professor Paolo Madeddu, Professor Massimo Caputo Bristol CardioVascular
Cognition and cerebrovascular changes in chronic renal disease Dr Catherine Pennington, Dr Phillip Clatworthy, Professor Patrick Kehoe Institute of Clinical Neuroscience
Identification, characterisation and functional assessment of microRNA regulation of foam cell macrophage formation during atherosclerosis progression Dr J Johnson, Dr K Di Gregoli Bristol CardioVascular
Understanding the neural substrates of treatment choice and treatment adherence in patients with chronic disease using a behavioural economic model Dr. N. Jade Thai, Dr. Naoki Masuda Clinical Research and Imaging Centre
Heparin infusions for enhanced glomerular barrier function in diabetic nephropathy Dr Becky Foster, Dr Simon Satchell Bristol Renal
Tissue engineering replacement grafts for corrective heart surgery using somatic stem cells Dr M Ghorbel, Prof M Caputo Bristol CardioVascular
Identification of biomarkers of progression to type 1 diabetes Kathleen Gillespie, Alistair Williams Diabetes and Metabolism
A holistic approach to unravel the problem of unfavourable ventriculo-arterial coupling: merging hemodynamic and molecular data> Dr G Biglino, Prof M Caputo Bristol CardioVascular
Understanding and curing genetic kidney disease Professor Moin Saleem, Dr Gavin Welsh Bristol Renal
Identifying the causes and cellular effects of Focal segmental glomerulosclerosis (FSGS) Dr Gavin WelshProfessor Moin Saleem Bristol Renal
Human parturition and Preterm labour: risk factors and regulatory mechanisms Professor A López Bernal, Dr GI Welsh Laboratories for Integrative Neuroscience and Endocrinology
Investigating the role of synuclein in Parkinson’s neurons Dr Liang-Fong Wong, Prof James Uney Bristol Neuroscience
Development and evaluation of interventions to improve care and support for pregnant women with previous bariatric surgery or obesity Dr Dimitrios Siassakos Obstetrics and Gynaecology
Alzheimer’s disease risk factor: Circadian regulation of synaptic function and neurodegeneration in the brain Professor Kei ChoDr Elizabeth Coultard, Dr Daniel Whitcomb and Professor Stafford Lightman Laboratories for Integrative Neuroscience and Endocrinology
Harnessing the proteinuria-reducing actions of Interferon beta to develop new treatments for kidney and cardiovascular disease Dr Simon Satchell, Dr Gavin Welsh Bristol Renal
Epigenetic factors that regulate hippocampal circuit assembly Dr Denize Atan, Prof Hans Reul Opthalmology
The role of adipose, abnormal fat storage and adipose related microenvironment changes in breast cancer Dr Claire Perks, Dr Sarah Dean, Prof Jeff Holly, Prof Julian Hamilton Shield IGFs and Metabolic Endocrinology Group
Investigating stem cells 3D bio printing and potential application in cardiovascular regenerative medicine Dr Mohamed Ghorbel, Prof Massimo Caputo Bristol CardioVascular
Smoking and preterm birth: mechanisms and consequences Prof Andres Lopez Bernal, Dr Gavin Welsh Laboratories for Integrative Neuroscience and Endocrinology
Investigating the therapeutic potential of newly identified gene targets using stem cell models of neurodegenerative disease Prof James Uney, Dr Liang Fong Wong Bristol Neuroscience
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