Spinning disk

Our Evident IXplore SpinSR system incorporates Yokogawa CSU-W1 SoRa spinning disk and enables super-resolution imaging.

Spinning disk microscopes offer an approach to confocal imaging which differs from more commonly used CLSM systems. In spinning disk systems, image detection by a camera is restricted to a single focal plane by an array of pinholes in a rapidly spinning disk which also distributes laser excitation across a field of view. Improved acquisition speed and lower peak power can offer advantages over CLSM systems for live imaging applications.

Evident IXplore IX83 SpinSR Technical Specifications (PDF, 213kB)

Advice with Large file handling (PDF, 88kB)

 

Recent papers including data acquired with our spinning disk system:

• Karling, Weavers. (2025) Immune cells adapt to confined environments in vivo to optimise nuclear plasticity for migration. EMBO Reports  doi: 10.1038/ s44319-025-00381-0
• Needs, Glover, Pereira, Witt, Hübner, Dodding, Henley, Collinson. (2024) Rescue of mitochondrial import failure by intercellular organellar transfer. Nature Communications 15(1):988.
• Daly, Danson, Lewis, Zhao, Riccardo, Di Filippo, Cacchiarelli, Lee, Cross, Heesom, Xiong, Ballabio, Edgar, Cullen. (2023) Multi-omic approach characterises the neuroprotective role of retromer in regulating lysosomal health (2023) Nature Communications 14(1):3086.
• Lu, Veler, Simonetti, Raj, Chou, Cross, Phillips, Ruan, Huynh, Dowsey, Ye, Murphy, Verkade, Cullen, Wülfing (2023) Five inhibitory receptors display distinct vesicular distributions in murine T cells. Cells 12(21):2558