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Fluorescent microscope image of healthy micro vessels in kidney tissue
Breakthrough blood test could detect heart and kidney disease earlier than ever before

A new way to detect the onset of heart and kidney disease far earlier than previously possible has been discovered by University of Bristol scientists. The breakthrough, published today [12 May] in Nature Communications, reveals a novel method for identifying damage to the lining of microscopic blood vessels, transforming our ability to detect disease at its very earliest stages, before it progresses and becomes potentially life threatening.

Age and gender impacts effectiveness of new gene therapy treatments for eye diseases, new study finds

Older women could be vulnerable to harmful inflammation from new gene therapies to treat incurable eye diseases, new research has found. The University of Bristol-led study, published in Molecular Therapy, reveal how age and gender affects inflammation caused by gene therapy treatments and could cause damage to the eye. The findings could help improve the therapy’s effectiveness for eye conditions and highlights the need for personalised treatment to reduce risk and ensure a better outcome for all patients.

Study highlights potential new approach for early intervention for diabetic patients at risk of kidney disease

Researchers at the University of Bristol have uncovered a mechanism by which a hormone can protect the blood vessels in the kidneys from the damage caused by diabetes. In doing so, the team has identified a potential early treatment strategy to prevent or slow progression of kidney disease in people with diabetes. The study, part-funded by Kidney Research UK, is published in Diabetes.

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