IEU Launch
MRC Integrative Epidemiology Unit at the University of Bristol
Launch event: 21st November, 2013
Leading the development of causal analysis methods for application in population-based and clinical health sciences.
The MRC Integrative Epidemiology Unit at the University of Bristol (IEU) establishes an innovative collection of programmes and cross-cutting themes, underpinned by core research activities to fuel a step-change in causal analysis methods and their application.
Substantial investment from both the UK Medical Research Council and the University of Bristol will provide resources for staff, research support and infrastructure to execute world-leading multi-disciplinary research in a vibrant, forward-looking environment. The IEU was officially launched on 21st November, 2013 by Professor Sir John Savill and Professor Sir Eric Thomas.
Final Programme (Office document, 107kB)
The Strategic Scientific Aims
- To apply novel causal methods for causal analyses developed in the IEU to key research questions related to a wide variety of health related outcomes.
- To ensure that novel causal methods for study design, data analysis and data collection developed in the MRC IEU are applied internationally outside of the IEU
- To develop exemplar methods and pioneering approaches for the secure and ethical sharing of large volumes of data for efficient and effective population health research.
University-wide contribution

Programme 1: George Davey Smith
Mendelian Randomization to Hypothesis Free Causal Inference
Programme 2: Caroline Relton
Epigenetic Epidemiology
Programme 3: Nicholas Timpson
Causal Analyses, Statistical Efficiency and Phenotypic Precision through Study Design: Recall by Genotype (RBG)
Programme 4: David Evans
Using Genetics to Identify Causal Pathways that Influence Bone Related Phenotypes in Children and Young Adults
Programme 5: Debbie Lawlor
Integrative Epidemiology in Relation to Reproductive and Cardiometabolic Health
Programme 6: Marcus Munafò
Determinants, Consequences and Modification of Health Behaviours
“The vision proposed by Professor Davey Smith and his team fits perfectly with the mission of the MRC to improve human health through world-class medical research.”
— Professor Sir John Savill, Chief Executive of the MRC
“Advances in genetics allow us to further our understanding of the many risk factors associated with poor health, and we are proud that this new partnership combined with our world-class research will help contribute to reduce the global burden of disease.”
— Professor Sir Eric Thomas, Vice Chancellor of the University of Bristol
Address: Oakfield House, Oakfield Grove, Bristol, BS8 2BN
Email: mrc-ieu@bristol.ac.uk