Title: "Stem Cells and Leukemia"

Background

Experiments in Dr. Eaves’ laboratory and elsewhere have established the existence in adults (both mouse and man) of primitive hematopoietic and breast stem cells capable of reconstituting these entire tissues. A major part of the work done by the Eaves laboratory continues to focus on the development, validation and use of quantitative assays that are specific for biologically distinct subsets of these stem cells using syngeneic (mouse-mouse) and xenogeneic (human-mouse) hosts, and the application of these technologies to understand the biological events that allow malignant clones to develop and progress.


For more information on Professor Eaves' research, please visit her institutional profile page.