Dr Ceire Costelloe Dr Sara Brookes (course organisers), Prof Colin Dayan, Dr Jeremy Horwood, Professor Will Hollingworth, Dr Athene Lane, Dr Chris Metcalfe, Professor Tim Peters, Dr Jelena Savovic, Joanne Simon, Dr Birgit Whitman Dr Alan Montgomery
Three days or five days depending on the option selected
£600 or £1000
The aim of the course is to provide an understanding of key issues in the design, analysis and reporting of clinical trials. The course focuses on randomised controlled trials in the evaluation of healthcare technologies. Observational epidemiological study designs, including cross-sectional, cohort and case-control studies, are not covered in this course.
By the end of the course, students should:
Anyone involved in the design, conduct, analysis or reporting of a randomised trial in the academic or NHS sector. Students will be expected to have a knowledge of statistical methods up to the level of the Introduction to Statistics course, and an understanding of research design up to the level of the Basic Epidemiology course. Basic knowledge of Stata is preferable but not essential for days 1-3,but a prerequisite for days 4 and 5.
Topics to be covered include: pragmatic and explanatory trials; hypothesis testing; clinical and statistical significance; sample size; randomisation; cluster trials; intention to treat analysis; alternative trial designs; multiple outcomes; repeated measures; adjustment for covariates; subgroup analysis; CONSORT guidelines on trial reporting; ethical issues in trials.
The course has been divided into two components. Day 1-3 will cover design elements of clinical trials with day 4 and 5 covering analysis of a trial dataset. Day 4 and 5 are optional and will require some STATA knowledge.
On application students should indicate if they are applying for
Teaching will make up a total of approximately 18 or 30 hours (depending on the option chosen), consisting of interactive-type lectures, problem-based learning in small groups and analyses of exemplar datasets using Stata.
For further information please contact firstname.lastname@example.org