View all news

Baby teeth may one day help identify kids at risk for mental disorders later in life

Press release issued: 10 November 2021

Like the rings of a tree, teeth contain growth lines that may reveal clues about childhood experiences. The thickness of growth marks in primary (or “baby”) teeth may help identify children at risk for depression and other mental health disorders later in life, according to a ground-breaking investigation led by researchers at Massachusetts General Hospital (MGH) using data from a world-renowned health study in Bristol.

The team analysed 70 primary teeth collected from 70 children enrolled in the Children of the 90s study. The results of this study could one day lead to the development of a much-needed tool for identifying children who have been exposed to early-life adversity, which is a risk factor for psychological problems, allowing them to be monitored and guided towards preventive treatments, if necessary.  

Exposure to sources of physical stress, such as poor nutrition or disease, can affect the formation of dental enamel and result in pronounced growth lines within teeth. One variety in particular, called the neonatal line (NNL), might serve as an indicator of whether an infant’s mother experienced high levels of psychological stress during pregnancy (when teeth are already forming) and in the early period following birth. Data from the study of the teeth and questionnaires completed by the mothers, demonstrated that children whose mothers had lifetime histories of severe depression or other psychiatric problems, as well as mothers who experienced depression or anxiety at 32 weeks of pregnancy, were more likely than other kids to have thicker NNLs.

Read the full University of Bristol press release

Further information

Paper: 'Association of Maternal Stress and Social Support During Pregnancy With Growth Marks in Children’s Primary Tooth Enamel' JAMA Network Open. Erin C. Dunn et al.

Edit this page