Our research

Our lab is primarily a wound healing lab and we work on several aspects of tissue repair. For the longest time we have been investigating how wounds re-epithelialise. Because we think inflammation drives scarring, we have been studying the wound inflammatory response. More recently we have begun to focus also on other cell lineages in wound repair.

And just as Harold Dvorak who famously said that “tumours are wounds that do not heal”, we have been drawn into studying parallels between wound and cancer inflammation.

David G found this picture of a zebrafish with a "suture" through its fin in a Leiden underpass - exactly what he works on!
Two stills from a movie (one minute apart) showing the moment when an immune cell (asterisked) passes through a hole in the basement membrane (green) en route to a cancer clone (confocal imaging with Imaris image analysis).
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