Malignant pleural effusions

A national randomised controlled trial comparing the effects of delivering talc slurry through an indwelling pleural catheter (IPC) with using an IPC alone. This study was published in 2018.

A national randomised controlled trial exploring the combination of talc slurry and pleural manometry with indwelling pleural catheters. This study is not yet published.

A first-in-human safety trial of a drug-eluting indwelling pleural catheter. This study was published in 2018.

A biobank and national randomised controlled trial examining if thoracic ultrasound can improve the success of talc pleurodesis. This study is not yet published.

A national randomised controlled trial comparing the effectiveness of chest drain and talc slurry with medical thoracoscopy and talc poudrage. This study was published in 2019.

A national randomised controlled trial comparing indwelling pleural catheters with chest drain and talc pleurodesis for managing breathlessness. This study was published in 2012.

A national randomised controlled trial exploring if intrapleural fibrinolytic is able to improve pleurodesis in patients with complicated malignant pleural effusion. This study was published in 2018.