Professor Lavinia Paternoster
BSc, MSc(Edin.), PhD
Expertise
Genetic Epidemiologist, currently working on genetics of eczema (atopic dermatitis) and genetics of disease progression (overcoming selection collider bias)
Current positions
Professor of Genetic Epidemiology
Epidemiology and Health Data Science
Contact
Press and media
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Research interests
I am a genetic epidemiologist working in the MRC Integrative Epidemiology Unit at the University of Bristol. My research is focused on the genetic aetiology of skin conditions.
I have led the EAGLE eczema consortium in several genome-wide association studies for eczema. I am also interested in subtypes of disease and have undertaken genetic studies of disease progression, severity and longitudinal trajectories. I now co-lead the Skin Genetics Consortium (skingeneticsconsortium.org) which leverages population scale genomic datasets to understand the genetic mechanisms underlying skin diseases and traits.
Key interests:
- Genome-wide association studies (GWAS)
- Target identification
- Mendelian Randomization for causal inference
- Genetics of disease progression
- Eczema and other skin conditions
Projects and supervisions
Research projects
Identifying causal risk factors for cognitive decline
Role
Co-Principal Investigator
Description
Takeda industry partner grant to examine causal risk factors for cognitive decline in the TOMMORROW trialManaging organisational unit
Bristol Medical School (PHS)Dates
01/11/2020 to 30/11/2022
Biomarkers in Atopic Dermatitis and Psoriasis
Principal Investigator
Managing organisational unit
Bristol Medical School (PHS)Dates
01/04/2019 to 31/03/2024
CLOSED 8073 MRC IEU - K.Berriman Studentship consumables - linked to Core
Principal Investigator
Managing organisational unit
Bristol Medical School (PHS)Dates
01/04/2018 to 30/09/2019
MRC IEU Studentship - Emily Jamieson
Principal Investigator
Managing organisational unit
Bristol Medical School (PHS)Dates
02/10/2017 to 01/10/2021
MRC - IEU studentship full - Alice Carter
Principal Investigator
Managing organisational unit
Bristol Medical School (PHS)Dates
03/10/2016 to 02/10/2020
Thesis supervisions
An Epigenome-Wide Association Study of Eczema
Supervisors
Describing the development of hip shape in adolescence, and environmental and genetic influences on this process, in ALSPAC offspring
Supervisors
Understanding the Role of Bone in the Pathogenesis of Osteoarthritis
Supervisors
Using genetic evidence to identify novel drug targets for the treatment of glioma
Supervisors
Causal implications of common infections and platelet function on cardiovascular disease
Supervisors
Publications
Selected publications
01/02/2012Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis
Nature Genetics
Recent publications
18/05/2026Circulating metabolites associated with psoriasis in the UK Biobank and the HUNT Study
The British journal of dermatology
Statistical Methods for Understanding Trajectories in Genetic Epidemiology
Annual Review of Biomedical Data Science
Childhood Allergy and Anxiety/Depression in Early Adulthood
Brain, Behavior, and Immunity
Gene-Environment Interaction Affects Risk of Atopic Eczema
Allergy: European Journal of Allergy and Clinical Immunology
Genetic inference of on-target and off-target side-effects of antipsychotic medications
PLOS Genetics
Teaching
Co-director of iBSc Genomic Medicine
Related people
Dr Raquel Granell
Research Fellow in Primary Care
Applied Health Research
Professor Celia Gregson
Professor in Clinical Epidemiology
Bristol Medical School
Professor George Davey Smith
Professor of Clinical Epidemiology
Epidemiology and Health Data Science
Dr Josine Min
Associate Professor
Epidemiology and Health Data Science
Professor Gibran Hemani
Professor in Statistical Genetics
Epidemiology and Health Data Science