Dr Dave Copland
B.Sc.(Bristol), MSc by Research, PhD
Current positions
Research Fellow
Bristol Medical School (THS)
Contact
Press and media
Many of our academics speak to the media as experts in their field of research. If you are a journalist, please contact the University’s Media and PR Team:
Research interests
- Mechanisms of innate immune cell activation and tissue damage in ocular inflammatory and neovascular conditions.
- Control of immune responses to promote/restore tissue homeostasis and function in the eye.
- In vivo ocular imaging, using Topical Endoscopic Fundal Imaging (TEFI), Fundal Fluorescein Angiography (FA) and Optical Coherence Tomography (OCT) platforms.
- Preclinical testing of novel therapeutic approaches using ocular disease models.
Projects and supervisions
Research projects
8066 NERC: Overcoming immune resPonses to retinal gene theropy
Principal Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
01/09/2021 to 31/08/2024
Overcoming immune responses to retinal gene therapy
Principal Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
06/01/2021 to 05/01/2024
Thesis supervisions
Publications
Recent publications
01/02/2024Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes
Cardiovascular Diabetology
Replenishing Age-Related Decline of IRAK-M Expression in Retinal Pigment Epithelium Attenuates Outer Retinal Degeneration
bioRxiv
Epigenetic drug screen identified IOX1 as an inhibitor of Th17-mediated inflammation through targeting TET2
EBioMedicine
Cellular senescence in the aging retina and developments of senotherapies for age-related macular degeneration
Journal of Neuroinflammation
Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses
Science Translational Medicine