International

Discovery of a druggable pocket in the SARS-CoV-2 Spike protein could stop virus in its tracks

A druggable pocket in the SARS-CoV-2 Spike protein that could be used to stop the virus from infecting human cells has been discovered by an international team of scientists led by the University of Bristol. The researchers say their findings, published today [21 September] in the journal Science, are a potential 'game changer' in defeating the current pandemic and add that small molecule anti-viral drugs developed to target the pocket they discovered could help eliminate COVID-19.

Do rats like to be tickled?

Not all rats like to be tickled but by listening to their vocalisations it is possible to understand in real-time their individual emotional response, according to new research by the University of Bristol. The study, published today [21 September] in Current Biology, suggests that if this same relationship is observed for other situations, then it may be possible to use call patterns in rats to measure their emotional response and understand how best to improve their welfare.