Bristol Medical School

Concern over unregulated high street health checks that may be putting extra pressure on the NHS

An investigation by the British Medical Journal (BMJ), highlights companies are offering private blood tests for a range of conditions and deficiencies, with some making misleading claims, not backed by evidence, and leaving an already overworked NHS to follow up “abnormal results". In a linked opinion article, experts from the Universities of Bristol and St Andrews highlight several areas of concern and argue that private blood testing companies need clear regulation to prevent more poor quality, over-hyped testing with harms to individuals and unnecessary costs for the NHS.

Association between poor sleep quality and an increased risk of developing Alzheimer's, new study finds

New research has shown an association between sleep quality – less than seven hours - and Alzheimer's disease-related pathology in people without cognitive impairment. The study by an international team led by the Pasqual Maragall Foundation research centre, the Barcelonaβeta Brain Research Centre (BBRC), together with researchers from the University of Bristol and North Bristol NHS Trust, is published in the scientific journal Brain Communications today [3 November].

Popular drug combination for treatment resistant depression is not more effective than a single antidepressant in primary care

Psychiatrists and GPs increasingly combine mirtazapine with an SSRI (selective serotonin reuptake inhibitor) or SNRI (serotonin-noradenaline reuptake inhibitor) antidepressant for patients whose depression does not respond to a single antidepressant. A large clinical trial led by researchers at the Universities of Bristol, Exeter, Keele, Manchester and Hull York Medical School, and published in the British Medical Journal today, looked at the effectiveness of adding mirtazapine to an SSRI or SNRI in patients who remain depressed after at least six weeks of conventional (SSRI or SNRI) antidepressant treatment. They found that this combination was no more effective in improving depression than placebo and call on doctors to rethink its use.