Bristol BioDesign Institute

Pocket feature shared by deadly coronaviruses could lead to pan-coronavirus antiviral treatment

Scientists have discovered why some coronaviruses are more likely to cause severe disease, which has remained a mystery, until now. Researchers of the University of Bristol-led study, published in Science Advances today [23 November], say their findings could lead to the development of a pan-coronavirus treatment to defeat all coronaviruses—from the 2002 SARS-CoV outbreak to Omicron, the current variant of SARS-CoV-2, as well as dangerous variants that may emerge in future.

Understanding natural fungicide synthesis: the pathway to strobilurins revealed at last

Scientists from the Universities of Bristol and Hannover studying a naturally-produced compound that inspired the biggest selling family of commercial agricultural fungicides have, for the first time, discovered how this important class of compound is synthesised in nature. The findings could potentially be used in the future to enable a ‘pick and mix’ approach with combinations of enzymes to make designer biosynthetic pathways for new compounds that could help to control crop diseases.