The NC3Rs Novel Bioprinters for 3D In vitro Models (3D-IV) project has developed three new bioprinters. The bioprinters combine a new approach to bioprinting developed at Newcastle University, reactive jet impingement (ReJI), with inkjet and microvalve bioprinting modes to create a unique bioprinter which offers new capabilities in terms of the creation of in vitro models. ReJI bioprinting can create gel cultures with high cell densities and can print on a wide variety of substrates. Inkjet printing gives the capability to print cells in solution at almost single cell resolution, whilst microvalve bioprinting can also cells in solution but to deposit high volumes. Together the three technique give a wide range of capabilities for creating 3D in vitro models using technologies which can support scale up when higher throughput is required.

This event is the first of three events, organised by Dr Deepali Pal of Bristol University, and will involve a demonstration of the bioprinting technology in the morning, followed by a research seminar on in vitro models in the afternoon. The seminar will focus on next generation 3D bioprinting for cancer disease modelling.

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