About the Integrative Cancer Epidemiology Partnership

Across the Integrative Cancer Epidemiology Partnership, our work builds on our world-leading expertise in causal analysis (specifically, Mendelian randomization) and population-based bioinformatics and genomic sciences. We use these methods to facilitate robust discrimination between causal exposures that are possible targets for behavioural or therapeutic interventions to prevent cancer (primary prevention) or its progression (tertiary prevention), from non-causal biomarkers which may nevertheless act as predictive biomarkers (secondary prevention).

Our key areas of expertise include: Mendelian randomization; molecular mechanisms; predictive biomarkers; and designing and evaluating interventions. This work is underpinned by strands in: Bioinformatics, AI and data mining; Evidence synthesis and triangulation; Capacity building; and Patient and public involvement and engagement (PPIE). Data sharing is prominent.

Since our cancer epidemiology work began in 2015, our work has helped increase understanding of cancer biology and improve prediction and early detection of cancer. Take a look at Our research journey to learn more about our work and its impact.

The partnership today includes the Obesity-related Cancer Epidemiology Programme as well as a range of other cancer epidemiology projects. We work together to share learning, provide support and continue the strong research culture formed through the previous programmes. ICEP sits alongside the University of Bristol's MRC Integrative Epidemiology Unit and within the University's cancer grand challenge. We work with partners all over the world.