Personality disorder

Personality disorder (PD) affects 4% of the adult population and the treatment of people with PD remains one of the most challenging areas in mental health. Research from our Centre  (Lead: Paul Moran) has highlighted the public health and economic burden of personality disorder and, by impacting on national guidelines, has helped to stimulate service development in a neglected clinical area.  

The personality disorders research theme spans epidemiological studies and translational research and we use a range of methods including observational studies, randomised controlled trials and mixed methods studies.

We have strong national and international collaborations, particularly with colleagues at King’s College London, Imperial College London, University College London, the University of Melbourne, and the Institute of Personality and Psychopathology in Denmark.

Selected current grants

  • Moran P, Weaver T, Barrett B, Trebilcock J, Khondoker M, Campbell C, Walker J, Forrester A, Logan C, Crawford M, Shaw J.  Ministry of Justice & NHS England.  Evaluation of the National Offender Personality Disorder (OPD) Pathway Programme. £793,163.  2017-19.
  • Moran P, Weaver T, Trebilcock J, Vollm B, Khondoker M, Campbell C, Jarrett M, Ministry of Justice & NHS England.  Evaluation of the Women’s Offender Personality Disorder (OPD) Pathway Programme.  £188,777. 2015- 2017
  • Day C, McCrone P, Michelson D, Moran P, Scott S, Stahl D, Ramchandani P, Crawford M, McMurran M Helping families: the systematic development and pilot RCT of a psychoeducational intervention for parents with personality disorders. NIHR.  £618,538. 2014-2017
  • Fonagy P, Butler, S, Bateman A, Yakeley J, Moran P, Crawford, McMurran M, Pilling S, Barrett B, Frater A, Hoare A, Wason J. Treatment of aggression and violence in anti-social personality disorder: a community-based randomised controlled trial of mentalization based treatment (TAV-ASPD). NIHR HTA. 2016-2020. £1,524,881.00.
  • Crawford M, Barrett B, Sanatinia R, Moran P, Morgan L. Low-intensity intervention for people with personality disorder: development of a practice-based protocol and feasibility study. NIHR RfPB.  2016-2019. £242,157. 

Selected publications

  • Pearson R, Campbell A, Howard L, Bornstein M, O’Mahen H, Mars B, Moran P. Impact of dysfunctional maternal personality traits on risk of offspring depression, anxiety and self-harm at age 18 years: a population-based longitudinal study. Psychological Medicine (in press).
  • French L, Turner K, Moran P.  Psychological treatment of depression and anxiety in patients with co-morbid personality disorder.  Personality & Mental Health  (in press).  
  • Hudson C, Spry E, Borschmann R, Becker D, Moran P, Olsson C, Coffey C, Romaniuk H, Bayer J, Patton G. Preconception personality disorder and antenatal maternal mental health: a population-based cohort study.  Journal of Affective Disorders (in press). 
  • Moran P, Romaniuk H, Coffey C, Chanen A, Degenhardt L, Borschmann R, Patton G (2016). The influence of personality disorder on the future mental health and social adjustment of young adults: a population-based cohort study.  Lancet Psychiatry Published first online June 21, 2016. http://dx.doi.org/10.1016/S2215-0366(16)30029-3.  
  • Quirk SA, Berk M, Pasco JA, Brennan-Olsen SL, Chanen AM, Koivumaa-Honkanen H, Burke L, Jackson HJ, Hulbert C, Olsson C, Moran P, Stuart AL, Williams LJ (2016). The prevalence, age distribution and comorbidity of personality disorders in Australian women.  Aus NZ J Psych.   Published online before print May 30, 2016, doi: 10.1177/0004867416649032.  
  • Du Preez A, Conroy S, Pawlby S, Moran P* and Pariante C* (2016). Differential effects of ethnic density on the risk of postnatal depression and personality dysfunction.  British Journal of Psychiatry; 208 (1) 49-55  * Joint senior author
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