The theme of the 2014 Annual BMS Meeting highlights the "Microcirculation as an Interactive Network" for communication between cells, vessels and the surrounding matrix & organ.
David Wynick is Professor of Molecular Medicine at the University of Bristol and Consultant Physician in Diabetes and Endocrinology at the Bristol Royal Infirmary, where he runs the regional painful diabetic neuropathy clinic.
His work combines basic-science with clinical research to better understand the mechanisms that cause neuropathic pain – this is pain caused by damage or injury to the nerves that transmit pain signals to the brain. This type of pain affects ~8% of the people in the Western World and places an enormous emotional and financial burden on patients, carers and society. Very few patients with neuropathic pain obtain complete pain relief with the drugs that are currently used to treat the condition and better and more effective long-term therapies are urgently required.
Over the last 15-years Professor Wynick and his group have identified and worked on a new neuropathic pain target using animal models of neuropathic pain. He has shown that during nerve injury, a small protein called galanin is released by the nervous system and appears to block the development of neuropathic pain. This research offers the potential for blocking neuropathic pain in humans and Professor Wynick’s research team are now moving from bench to bedside by developing a novel drug suitable for human use to block the galanin receptor that mediates the analgesic effects of galanin.
Professors Wynick’s lecture will describe how his exciting discoveries about galanin may help doctors provide better treatments in the future for neuropathic pain.
No booking required, for further information please contact Debora Kay (email@example.com or +44 (0)117 331 2265)
Download the 2014 SiPPs Autumn Timetable (PDF 689kb)
If you would like to meet a visiting speaker or have any queries, please contact Dr Ingeborg Hers (I.Hers@bristol.ac.uk) or Dr Andy Salmon (firstname.lastname@example.org)
Supported by The Physiological Society
Supported by The Physiological Society and British Neuroscience Association
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