Software
Researchers at the MRC IEU have created a range of openly available software tools based on research methods developed within the Unit.
MendelVar
MendelVar performs enrichment of ontology terms amongst genes linked to Mendelian disorders within genomic intervals.
EpiGraphDB
EpiGraphDB integrates epidemiological and biomedical data to support mechanistic and causal inference
IEU GWAS database
IEU GWAS database contains thousands of publicly available GWAS for download or use in MR-Base
MR Base
MR Base enables online Mendelian randomization analysis using a comprehensive manually curated database of GWAS studies.
LD Hub
LD Hub supports online LD score regression analysis using a comprehensive manually curated database of GWAS studies.
MELODI
MELODI is a literature mining platform to identify potential mechanistic pathways between exposures and disease outcomes.
FATHMM
FATHMM predicts the functional effects of genetic variants in coding and non-coding parts of the genome.
mQTLdb
mQTLdb is a database of methylation QTL (mQTL) from different stages across the lifecourse.
Genome Tolerance Browser
Genome Tolerance Browser (GTB) visually compares functional prediction algorithms across the genome.
TeMMPo
TeMMPo is a literature search tool to quantify the literature for specific disease mechanism.
RbG Study Planner
RbG study planner assists in the planning stages and power assessment of recall by genotype studies.
IEU GitHub site
Find a range of software on the MRC-IEU GitHub site
HIPred
An integrative approach to predicting haploinsufficient genes
Meffil
Efficient algorithms for analyzing DNA methylation data
PHESANT
Package to run a phenome scan in UK Biobank
TwoSampleMR (MR-Base)
The R package for MR-Base