Researchers at the MRC IEU have created a range of openly available software tools based on research methods developed within the Unit.
MR Base enables online Mendelian randomization analysis using a comprehensive manually curated database of GWAS studies.
LD Hub supports online LD score regression analysis using a comprehensive manually curated database of GWAS studies.
MELODI is a literature mining platform to identify potential mechanistic pathways between exposures and disease outcomes.
FATHMM predicts the functional effects of genetic variants in coding and non-coding parts of the genome.
mQTLdb is a database of methylation QTL (mQTL) from different stages across the lifecourse.
Genome Tolerance Browser (GTB) visually compares functional prediction algorithms across the genome.
TeMMPo is a literature search tool to quantify the literature for specific disease mechanism.
An integrative approach to predicting haploinsufficient genes
Efficient algorithms for analyzing DNA methylation data
Package to run a phenome scan in UK Biobank