Software

Researchers at the MRC IEU have created a range of openly available software tools based on research methods developed within the Unit.

MR Base

MR Base enables online Mendelian randomization analysis using a comprehensive manually curated database of GWAS studies.

LD Hub

LD Hub supports online LD score regression analysis using a comprehensive manually curated database of GWAS studies.

MELODI

MELODI is a literature mining platform to identify potential mechanistic pathways between exposures and disease outcomes.

FATHMM

FATHMM predicts the functional effects of genetic variants in coding and non-coding parts of the genome.

mQTLdb

mQTLdb is a database of methylation QTL (mQTL) from different stages across the lifecourse.

Genome Tolerance Browser

Genome Tolerance Browser (GTB) visually compares functional prediction algorithms across the genome.

TeMMPo

TeMMPo is a literature search tool to quantify the literature for specific disease mechanism. 

RbG Study Planner

RbG study planner assists in the planning stages and power assessment of recall by genotype studies.

HIPred

An integrative approach to predicting haploinsufficient genes

Meffil

Efficient algorithms for analyzing DNA methylation data

PHESANT

Package to run a phenome scan in UK Biobank

TwoSampleMR (MR-Base)

The R package for MR-Base

Edit this page