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Unit information: Coronary Artery Disease I in 2024/25

Please note: Programme and unit information may change as the relevant academic field develops. We may also make changes to the structure of programmes and assessments to improve the student experience.

Unit name Coronary Artery Disease I
Unit code SOCSM0003
Credit points 20
Level of study M/7
Teaching block(s) Teaching Block 1 (weeks 1 - 12)
Unit director Professor. Johnson
Open unit status Not open
Units you must take before you take this one (pre-requisite units)

None

Units you must take alongside this one (co-requisite units)

None

Units you may not take alongside this one

None

School/department Bristol Medical School
Faculty Faculty of Health Sciences

Unit Information

Why is this unit important?

This unit will introduce the clinical problem of coronary artery disease, which is the cause of around 10% of all deaths in the UK. Coronary artery disease is the most commonly diagnosed cardiovascular disease worldwide, with around 200 million people living with the disease. Since coronary artery disease has such a large impact on global morbidity and mortality, it is vital that we understand the underlying pathobiology of atherosclerosis, which causes this disease. This unit will provide a detailed overview of the underlying processes driving atherosclerosis, and teach you how animal models can be used to further understand the pathophysiology. Learning about the pathophysiology will allow you to understand the mechanism of currently used drug treatments for coronary artery disease, and appreciate how new therapeutics can be discovered and developed for clinical application. This unit will also include academic skills training, enabling you to succeed in your academic endeavours.

How does this unit fit into your programme of study?

This unit is taken at the beginning of the programme and precedes Coronary Artery Disease II. Understanding the fundamentals of the epidemiology, diagnosis, pathophysiology and pharmacological treatment of this disease will allow you to learn about additional treatments in Coronary Artery Disease II. Atherosclerosis also contributes to the development of peripheral arterial disease, carotid artery disease and some forms of aortic aneurysm, which will be covered later in the MSc programme (Aneurysm, Peripheral Vascular Disease & Stroke). You will learn about research techniques to study atherosclerosis, including animal models, which can be applied during the Research Project unit (MSc students only). Furthermore, academic skills training will prepare you for subsequent study.

Your learning on this unit

An overview of content

The unit provides a detailed overview of the underlying processes driving atherosclerosis, including endothelial cell dysfunction, inflammation, smooth muscle cell behaviour, plaque rupture, thrombosis and vessel occlusion. This will help you understand the currently used drug treatments for coronary artery disease, and the animal models utilised to further understand the pathophysiology of atherosclerosis and evaluate potential new therapeutics.

The unit provides you with an overview of the methods currently utilised for patient diagnosis and assessment of disease severity (from GP to clinic), such as ECG, angiogram, imaging and identification of biomarkers. We will also study the disease epidemiology and discuss common risk factors (including hypercholesterolemia, hypertension, diabetes, smoking). Integrated into this unit is skills training, including academic writing; reading, interpreting and presenting clinical and scientific literature.

How will students, personally, be different as a result of the unit?

Coronary artery disease is the first cardiovascular disease covered on our programme; teaching on this unit will help you understand the complexity of disease pathology and allow you to appreciate the contribution and behaviour of many different cell types involved in disease development and progression. This knowledge will provide a good foundation for learning about other cardiovascular diseases within the following units. This unit exposes you to the cutting-edge atherosclerosis research within our department and beyond, and may inspire you to pursue further research on this topic.

Learning Outcomes

After successfully completing this unit you will be able to:

  1. Describe the epidemiology of coronary artery disease and discuss its main risk factors.
  2. Discuss the methods currently utilised for clinical assessment of patients with suspected coronary artery disease.
  3. Explain the pathobiology of atherosclerosis and critically evaluate the pre-clinical and clinical evidence that has aided our understanding of this disease.
  4. Discuss the current pharmacological treatments used for coronary artery disease patients.

How you will learn

The core content will be delivered via in-person lectures (campus students) or lecture recordings (online students). Lecture recordings will be available to all students so you can review the lecture material multiple times at your own pace, with the inclusion of captions. Lectures will be supplemented with additional teaching methods such as:

  • Interactive tutorials including small group discussions and activities; some of these tutorials are designed to help directly with coursework assessments, while others may explore a unit topic in more depth. All tutorial resources will be available online following the campus teaching.
  • Asynchronous discussion/input via message boards/Padlets – these allow students to collaboratively contribute to knowledge on a unit-specific topic.
  • Workshops to highlight unit-specific research skills and related data analysis – these help students understand the research evidence presented during teaching.
  • Lectures, tutorials and workshops will often include anonymised quizzes and MCQs which provide instant formative feedback to students.
  • Self-directed study.

Students will be given formative feedback on all coursework assessments to aid their learning.

How you will be assessed

Tasks which help you learn and prepare you for summative tasks (formative):

  • Short essay due at the start of the unit which is used for guidance on good academic practice during academic skills training. Generic and individual written feedback will be provided to use for subsequent written assessments such as the summative essay in this unit.
  • Bullet point plan for the summative essay, including a description of the strategy used to search for and filter relevant information. Individual written feedback will be provided to reassure students that they have included appropriate breadth of content and associated evidence. The formative plan will be submitted mid unit.
  • Tutorial to prepare for ‘public information media piece’ assessment involving group activities and discussion. The details of the assignment and marking criteria will be explained, and students will be given collective, verbal feedback on their ideas.

Tasks which count towards your unit mark (summative):

  • Multiple choice questions (MCQs), submitted at the end of the unit to review and test your knowledge of the unit core content (ILOs 1-4). These will contribute 10% to the unit mark.
  • Public information media piece (e.g. leaflet, poster, website, podcast or videocast) on unit-specific topic (ILOs 1,2 and 4), submitted towards the end of the unit. This will contribute 40% to the unit mark.
  • Essay plus a reflection on your academic process, on a topic related to ILO3. This will be submitted at the end of the unit and will contribute 50% to the unit mark.

When assessment does not go to plan:

If you do not pass the unit, you will normally be given the opportunity to take a reassessment as per the Regulations and Code of Practice for Taught Programmes. Decisions on the award of reassessment will normally be taken after all taught units of the year have been completed. Reassessment will normally be in a similar format to the original assessment that has been failed.

Resources

If this unit has a Resource List, you will normally find a link to it in the Blackboard area for the unit. Sometimes there will be a separate link for each weekly topic.

If you are unable to access a list through Blackboard, you can also find it via the Resource Lists homepage. Search for the list by the unit name or code (e.g. SOCSM0003).

How much time the unit requires
Each credit equates to 10 hours of total student input. For example a 20 credit unit will take you 200 hours of study to complete. Your total learning time is made up of contact time, directed learning tasks, independent learning and assessment activity.

See the University Workload statement relating to this unit for more information.

Assessment
The Board of Examiners will consider all cases where students have failed or not completed the assessments required for credit. The Board considers each student's outcomes across all the units which contribute to each year's programme of study. For appropriate assessments, if you have self-certificated your absence, you will normally be required to complete it the next time it runs (for assessments at the end of TB1 and TB2 this is usually in the next re-assessment period).
The Board of Examiners will take into account any exceptional circumstances and operates within the Regulations and Code of Practice for Taught Programmes.

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