Idiopathic Pulmonary Fibrosis

Studies & trials

A role for cardiopulmonary exercise testing in detecting physiological changes underlying health
A longitudinal study evaluating the prognostic role of cardiopulmonary exercise testing in patients with IPF. This study has been published.
Description of Palliative Care Models in ILD Clinics and their impact on IPF care*
A multi-centre retrospective study comparing novel palliative care models and their impact on IPF care. This study is currently open.
The Role of Vascular endothelial growth factor in the development of IPF*
A basic science and translational study examining the biological pathways underpinning the development of IPF. This study has been published.
CELGENE
A Phase II randomised placebo controlled multi-centre study of the use of CC-90001 in patients with IPF. This study has completed recruitment but is not yet published.
INMARK
A multicentre study of biomarkers of extracellular matrix turnover in IPF. This study has been published
Drug to drug interaction in IPF
Open label phase 4 study investigating the pharmacokinetic drug-drug interaction between Nintedanib and Pirfenidone in Idiopathic Pulmonary Fibrosis. This study has been published
INSTAGE
Randomised controlled trial investigating combined use of nintedanib and sildenafil compared to nintedanib alone, in patients with IPF. This study has been published
GALACTIC
A randomised, double-blind, placebo-controlled phase 2b trial in subjects with IPF investigating the efficacy and safety of TD139. This study has completed recruitment but is not yet published.
TIPAL
The effectiveness and risks of Treating people with Idiopathic Pulmonary fibrosis with the Addition of Lansoprazole, a randomised placebo-controlled multi-centre clinical trial.
MABEL
A parallel group, double-blind, randomised, placebo-controlled trial comparing the effectiveness and cost effectiveness of low dose oral modified release morphine versus placebo on patient-reported worst breathlessness in people with chronic breathlessness.