We are conducting state-of-the-art research using stem cells, organoids, biomaterials, and biotechnologies to grow artificial living tissues and develop new regenerative therapies. This research covers a diverse range of tissues (e.g., cartilage, bone, muscle, heart, brain) and encompasses interdisciplinary methods from engineering, chemistry, and biology. Through international collaboration and partnerships with local clinicians, we are focused on producing translational grafts for clinical application as well as advanced biological models that can be used to understand development, disease, and drug response.
Tissue Engineering and Regenerative Medicine
It is an exciting time to be working in regenerative medicine and tissue engineering: the maturation of advanced biological manipulation (iPSCs, CRISPR, organoids, single cell sequencing) and the development of new bioengineering tools (organ-on-chip, bioreactors, smart biomaterials) is leading to unprecedented advances in our quest to understand and harness biological systems for tissue repair.
Figure 1
Regenerative medicine is a broad science using synergistic combinations of cells, biomaterials, and biomolecules to repair, replace, and rejuvenate damaged tissues (figure from JPK Armstrong et al. “A Blueprint for Translational Regenerative Medicine” Science Translational Medicine 2020).
Contact us
Dr James Armstrong
Office 2.08, Dorothy Hodgkin Building, Whitson Street, Bristol, BS1 3NY