Relevant publications

QUADAS-3

• Whiting PF, Tomlinson E, Rutjes AWS, et al. QUADAS-3: A revised tool for the quality assessment of diagnostic test accuracy studies. Ann Intern Med. 17 February 2026. [Epub ahead of print]. doi:10.7326/ANNALS-25-02104
• Davenport CF, Rutjes AWS, Mallett S, et al. QUADAS-3 explanation and elaboration: guidance for quality assessment of diagnostic test accuracy studies. Ann Intern Med. 2026;178:e2504943. doi:10.7326/ANNALS-25-04943
• Tomlinson E, Yang B, Davenport CF, et al. Piloting QUADAS-3: A revised tool for the quality assessment of diagnostic accuracy studies. J Clin Epidemiol. 2025;188:111983
• Tomlinson E, Holmes J, Rutjes AWS, et al. Developing a framework for assessing the applicability of the target condition in diagnostic research. J Clin Epidemiol. 2026;190:112059. 

QUADAS-C

• Yang B, Mallett S, Takwoingi Y, et al; QUADAS-C Group. QUADAS-C: A tool for assessing risk of bias in comparative diagnostic accuracy studies. Ann Intern Med. 2021;174:1592-1599. 

QUADAS-2

• Whiting PF, Rutjes AWS, Westwood ME, Mallett S, Deeks JJ, Reitsma JB, Leeflang MM, Sterne JAC, and Bossuyt PMM. QUADAS-2: A Revised Tool for the Quality Assessment of Diagnostic Accuracy Studies. Ann Intern Med 155 (8):529-536, 2011.
• Evidence report prepared for QUADAS-2 face-to-face meeting.  Updating QUADAS: Evidence to inform the development of QUADAS-2 (PDF, 2,877kB)

QUADAS

• Whiting P, Rutjes A, Reitsma J, Bossuyt P, Kleijnen J. The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews. BMC Med Res Methodol. 2003 Nov 10;3:25
• Whiting P, Rutjes A, Dinnes J, Reitsma J, Bossuyt P, et al. Development and validation of methods for assessing the quality of diagnostic accuracy studies. Health Technol Assess 2004;8(25).