
Professor Vikki Wylde
B.Sc.(Bristol), PhD
Current positions
Professor of Musculoskeletal Health
Bristol Medical School (THS)
Contact
Press and media
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Research interests
I am a health services researcher with an interest in improving the health and wellbeing of people living with chronic musculoskeletal conditions. I conduct research that spans the translational pathway and impacts on patient care through informing NICE guidance and changing NHS practice. My research aims to improve patients’ outcomes and experiences of interventions for musculoskeletal pain, with a particular focus on evaluating interventions to optimise outcomes after orthopaedic surgery, such as hip and knee replacement. I am committed to ensuring that health research is inclusive, through involvement of patients and communities in all stages of the research process.
I currently lead the RADICAL trial, a NIHR HTA-funded randomised trial evaluating the clinical and cost-effectiveness of radiofrequency denervation for chronic low back pain. I am also Chief Investigator on the Joint PREP study, a NIHR RfPB-funded feasibility study for a randomised trial evaluating pre-operative exercise and nutrition for frail patients undergoing hip and knee replacement. I am Joint Lead Applicant on a RfPB-funded project to develop a care plan for patients having knee replacement. Other NIHR-funded research that I am involved in covers topics such as patellar resurfacing, implant type for hip replacement, injections for osteoarthritis, sleep and implementing research findings into NHS practice. I am Co-Theme Lead for Surgical and Orthopaedic Innovation in the Bristol Biomedical Research Centre.
For the MSc in Orthopaedic Research Methods and Evidence-Based Medicine, I am Lead for the Research Projects Unit. In the iBSc in Clinical Sciences, I co-lead a Unit on clinical research methods in chronic diseases.
Projects and supervisions
Research projects
A co-production film project with the older South Asian community to promote inclusive involvement in health research
Principal Investigator
Role
Co-Principal Investigator
Description
For two and a half years, we have been working with Dhek Bhal a South Asian community group in Bristol, on research about bones and joints and about making health…Managing organisational unit
Bristol Medical School (THS)Dates
01/01/2024 to 31/07/2024
NIHR Programme Development Grants (NIHR202943) Infection and Orthopaedic Management: Mobilising evidence into practice
Principal Investigator
Role
Co-Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
01/07/2021 to 30/06/2023
Feasibility study for a randomised controlled trial of one-stage or two-stage surgery for prosthetic knee infection
Role
Co-Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
01/07/2020 to 01/07/2022
RecUrrent Intra-articular Corticosteroid injections in Osteoarthritis; the RUbICOn study
Principal Investigator
Role
Principal Investigator
Description
Osteoarthritis is a condition that causes joints to become painful and stiff, it is a common cause of pain
and disability. Management of osteoarthritis involves reducing pain and maintaining function. Simple…Managing organisational unit
Bristol Medical School (THS)Dates
01/03/2020 to 31/08/2022
NIHR Health Technology Assessment (NIHR127457) Radiofrequency denervation for chronic and moderate to severe low back pain: The RADICAL trial.
Principal Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
01/01/2020 to 31/12/2024
Thesis supervisions
Publications
Recent publications
14/02/2025Amitriptyline for the prevention of post-herpetic neuralgia
Skin Health and Disease
Facilitating translation of trial findings into NHS practice
Bone and Joint Open
Protocol for systematic review: Patients’ and surgeons’ preferences for primary total hip replacement outcomes
An opportunity to sleep well in hospital
BMC Psychology
Effectiveness and cost-effectiveness of radiofrequency denervation versus placebo for chronic and moderate to severe low back pain
BMJ Open
Thesis
The role of pre-operative pain sensitisation in chronic pain after knee replacement
Supervisors
Award date
01/01/2010