Dr Vikki Wylde
Associate Professor in Musculoskeletal HealthBristol Medical School (THS)
Press and media
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I am a health services researcher with an interest in improving the health and wellbeing of people living with chronic musculoskeletal conditions. I conduct research that spans the translational pathway and impacts on patient care through informing NICE guidance and changing NHS practice. My research aims to improve patients’ outcomes and experiences of interventions for musculoskeletal pain, with a particular focus on evaluating interventions to optimise outcomes after orthopaedic surgery, such as hip and knee replacement. I am committed to ensuring that health research is inclusive, through involvement of patients and local communities in all stages of the research process.
I currently lead the RADICAL trial, a NIHR HTA-funded randomised trial evaluating the clinical and cost-effectiveness of radiofrequency denervation for chronic low back pain. I am also Chief Investigator on the Joint PREP study, a NIHR RfPB-funded feasibility study for a randomised trial evaluating pre-operative exercise and nutrition for frail patients undergoing hip and knee replacement. I am Joint Lead Applicant on a RfPB-funded project to develop a care plan for patients having knee replacement. Other NIHR-funded research that I am involved in covers topics such as patellar resurfacing, implant type for hip replacement, injections for osteoarthritis, sleep and implementing research findings into NHS practice. I am Co-Theme Lead for Surgical and Orthopaedic Innovation in the Bristol Biomedical Research Centre.
For the MSc in Orthopaedic Research Methods and Evidence-Based Medicine, I am Lead for the Research Projects Unit. In the iBSc in Clinical Sciences, I co-lead a Unit on clinical research methods in chronic diseases.
Projects and supervisions
NIHR Programme Development Grants (NIHR202943) Infection and Orthopaedic Management: Mobilising evidence into practice
01/07/2021 to 30/06/2023
Feasibility study for a randomised controlled trial of one-stage or two-stage surgery for prosthetic knee infection
01/07/2020 to 01/07/2022
RecUrrent Intra-articular Corticosteroid injections in Osteoarthritis; the RUbICOn study
DescriptionOsteoarthritis is a condition that causes joints to become painful and stiff, it is a common cause of pain
and disability. Management of osteoarthritis involves reducing pain and maintaining function. Simple…
01/03/2020 to 31/08/2022
NIHR Health Technology Assessment (NIHR127457) Radiofrequency denervation for chronic and moderate to severe low back pain: The RADICAL trial.
01/01/2020 to 31/12/2024
Development of evidence-based guidelines for the treatment and management of periprosthetic hip infection
Bone & joint open
Healthcare professionals’ views on implementing the STAR care pathway for people with chronic pain after total knee replacement
Rehabilitation for revision total knee replacement
BMC Musculoskeletal Disorders
The effectiveness of non-pharmacological sleep interventions for improving inpatient sleep in hospital: a systematic review and meta-analysis
- E-pub ahead of print
Cost-Effectiveness of Group-Based Outpatient Physical Therapy After Total Knee Replacement
Arthritis Care and Research
The role of pre-operative pain sensitisation in chronic pain after knee replacement