Professor Emma Raven
BSci (Leic.), PhD(N'cle)
Current positions
Head of School
School of ChemistryProfessor
School of Chemistry
Contact
Media contact
If you are interested in speaking to this expert, contact the University’s Media & PR Team on
Research interests
The work of my research is to understand the catalytic activity and biological function in heme containing enzymes. Heme is the prosthetic group found in a number of biologically important proteins (from haemoglobin to catalases) which have a diverse range of biological functions including electron transfer, transportation of gases and chemical catalysis. Our work is focused in three main areas: peroxidases, dioxygenases and the role of heme in the cell. We use kinetic and spectroscopic methods to understand the mechanism and function of heme enzymes, and we collaborate with structural biologists (Prof Peter Moody, University of Leicester) to provide a structural framework for our experiments.
Projects and supervisions
Research projects
BBSRC International Partnerships Fund
Principal Investigator
Managing organisational unit
School of ChemistryDates
01/11/2022 to 31/03/2023
Understanding supply and demand for heme in cells
Principal Investigator
Managing organisational unit
School of ChemistryDates
01/04/2022 to 31/03/2026
8082 BBSRC Japan Partnering award BB/S020586/1
Principal Investigator
Managing organisational unit
School of ChemistryDates
01/07/2019 to 30/06/2023
A Bristol-RIKEN partnership to exploit the SACLA free electron laser
Principal Investigator
Description
The aim of this application is to establish a long-term collaboration with the groups at Spring-8/Hyogo University. Spring-8 is the world’s largest third generation synchrotron facility and the home of…Managing organisational unit
School of ChemistryDates
01/05/2019 to 31/07/2019
A structural framework for understadning Chagas disease
Principal Investigator
Managing organisational unit
School of ChemistryDates
01/08/2018 to 30/06/2022
Thesis supervisions
Publications
Recent publications
01/12/2021Binding of l-kynurenine to X. campestris tryptophan 2,3-dioxygenase
Journal of Inorganic Biochemistry
Understanding the Logistics for the Distribution of Heme in Cells
Journal of the American Chemical Society
Unravelling the mechanisms controlling heme supply and demand
Proceedings of the National Academy of Sciences of the United States of America
XFEL Crystal Structures of Peroxidase Compound II
Angewandte Chemie - International Edition
Heme peroxidase—Trapping intermediates by cryo neutron crystallography
Methods in Enzymology