Dr Darryl Hill
Associate Professor in Infectious DiseasesSchool of Cellular and Molecular Medicine
Bacterial infections of the respiratory tract which lead to localised or disseminated disease are a considerable health and financial burden globally. Our research focuses on understanding the interplay between bacteria (mainly colonisers of the respiratory tract) and their human host during colonisation and progression of disease. By understanding key mechanisms used by bacteria to interact with human cells and tissues therapeutic targets can be identified.
- Molecular basis of receptor targeting by mucosal pathogens which colonise the human nasopharynx and oropharynx. Principally studies focus on Neisseria meningitidis, Moraxella catarrhalis and Haemophilus influenzae.
- Interactions of Neisseria meningitidis with serum components.
- Epithelial cell responses to neisserial infection.
- Bacterial interplay during adhesion to human respiratory epithelia.
- Structure and function analyses of Moraxella catarrhalis surface proteins.
- Bacterial-stem cell interactions in osteomyelitis.
- Professor Neil Williams (CMM)
- Professor Adam Finn (Institute of Child Health Bristol/CMM)
- Professor Leo Brady (Biochemistry, University of Bristol)
- Professor Charles Serhan (Harvard Medical School)
- Dr Wael Kafienah (CMM)
- Dr Eric Lafontaine (University of Georgia)
- Dr Dave Dymock (Oral and Dental Sciences, University of Bristol)
- Dr Nathan Zaccai (Biochemistry, University of Bristol)
- Dr Richard Sessions (Biochemistry, University of Bristol)
01/07/2020 to 31/03/2021
Managing organisational unitSchool of Biochemistry
01/11/2019 to 30/06/2022
01/01/2019 to 01/05/2019
01/03/2017 to 31/05/2017
- Accepted/In press
Mucin transiently sustains coronavirus infectivity through heterogenous changes in phase morphology of evaporating aerosol
Rapid detection of Neisseria gonorrhoeae genomic DNA using gold nanoprobes which target the gonococcal DNA uptake sequence
Frontiers in Cellular and Infection Microbiology
- Accepted/In press
Proceedings of the National Academy of Sciences of the United States of America
- E-pub ahead of print
Aerosol Science and Technology