International

Prescribing antibiotics for children with cough in general practice does not reduce hospitalisation risk

Doctors and nurses often prescribe antibiotics for children with cough and respiratory infection to avoid return visits, symptoms getting worse or hospitalisation. In a study published in the British Journal of General Practice today [Tuesday 11 September], researchers from the Universities of Bristol, Southampton, Oxford and Kings College London found little evidence that antibiotics reduce the risk of children with cough ending up in hospital, suggesting that this is an area in which unnecessary antibiotic prescribing could be reduced.
Understanding natural fungicide synthesis: the pathway to strobilurins revealed at last

Scientists from the Universities of Bristol and Hannover studying a naturally-produced compound that inspired the biggest selling family of commercial agricultural fungicides have, for the first time, discovered how this important class of compound is synthesised in nature. The findings could potentially be used in the future to enable a ‘pick and mix’ approach with combinations of enzymes to make designer biosynthetic pathways for new compounds that could help to control crop diseases.
Incarceration is likely to increase HIV and HCV transmission among people who inject drugs, new study finds

Injecting drug use, through the sharing of needles, syringes and other injecting equipment, is a primary route of transmission for both HIV and hepatitis C virus (HCV), blood-borne infections that cause considerable morbidity and mortality worldwide. New research led by the University of Bristol has found among people who inject drugs, that recent incarceration was associated with an 81 per cent and 62 per cent increase in HIV and HCV acquisition risk, respectively.