Bristol Population Health Science Institute

Pfizer-BioNTech and AstraZeneca vaccines offer high protection against severe COVID-19, six months after second doses, study finds

Protection against severe COVID-19 by two doses of Pfizer-BioNTech and AstraZeneca COVID-19 vaccines remained high up to six months after second doses, finds new research which analysed NHS health record data on over seven million adults. Reassuringly, the University of Bristol-led study published in The BMJ today [July 20], found protection in older adults aged over 65 years, and in clinically vulnerable adults.

Scientists discover genes that affect the risk of developing pre-leukaemia

The discovery of 14 inherited genetic changes which significantly increase the risk of a person developing a symptomless blood disorder associated with the onset of some types of cancer and heart disease is published today [July 14] in Nature Genetics. The finding, made in one of the largest studies of its kind through genetic data analysis on 421,738 people, could pave the way for potential new approaches for the prevention and early detection of cancers including leukaemia.

Incarceration is likely to increase HIV and HCV transmission among people who inject drugs, new study finds

Injecting drug use, through the sharing of needles, syringes and other injecting equipment, is a primary route of transmission for both HIV and hepatitis C virus (HCV), blood-borne infections that cause considerable morbidity and mortality worldwide. New research led by the University of Bristol has found among people who inject drugs, that recent incarceration was associated with an 81 per cent and 62 per cent increase in HIV and HCV acquisition risk, respectively.