Hosted by the School of Medicine at Cardiff University

Allon Klein, an Associate Professor of Systems Biology at Harvard Medical School, is recognised as a pioneer in high-throughput approaches to single-cell biology. His work includes multiple technical and computational innovations, and the discovery of new cell types. He is a co-recipient of the inaugural James Prize for Science and Technology Integration from the US National Academy of Sciences, among other awards. Klein's development of high-throughput technologies has revolutionised our understanding of cellular diversity in tissue biology. He earned his PhD in Physics from Cambridge University. The Klein Lab is developing quantitative assays, innovative genomic technology, statistical tools, and theory to address the following questions: 

• How do cells with the same genome differentiate into distinct types? 
• What measurements on stem cells and developing tissues will help us answer this question? 

The Klein Lab has introduced droplet microfluidics for single cell genomics, and a range of computational tools to analyze developmental dynamics from single cell RNA-Seq data sets. They develop statistical approaches to analyze the live cell dynamics, and experimental methods for long-term live imaging.

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